Results 61 to 70 of about 10,177 (227)

Systematically Engineering for Efficient Production of 3‐Methyl‐1‐Butanol in Escherichia coli

Advanced Science, EarlyView.
An integrated metabolic engineering strategy was established for high‐level 3‐methyl‐1‐butanol biosynthesis in Escherichia coli. Molecular dynamics‐guided semi‐rational engineering of dihydroxyacid dehydratase uncovered and relieved key catalytic bottlenecks, while adaptive laboratory evolution enhanced strain robustness.
Nanfei Geng, Hao Liu, Haolin Han, Meng Meng, Shaojie Wang, Tianwei Tan, Haijia Su   +6 more
wiley   +1 more source

The Function of Cyclo(Phe-Pro) in Gene Expression of Vibrio Harveyi [PDF]

, 2012
Vibrio harveyi is a bioluminescent bacterium and the organism in which quorum sensing was discovered. It was recently found that a class of molecules, cyclic dipeptides, may be a new kind of quorum sensing signal that may affect other species in the ...
Milburn, Bruce
core  

Electron scattering from molecules and molecular aggregates of biological relevance [PDF]

, 2017
In this Topical Review we survey the current state of the art in the study of low energy electron collisions with biologically relevant molecules and molecular clusters.
Allan M, Allan M, Bouchiha D, Calegari F, Caprasecca S, Colyer C J, Colyer C J, da Costa R F, Denifl S, Dora A, Dubernet M L, Fabrikant I I, Fabrikant I I, Ferlay J, Fujimoto M M, Hall E, Herbert J M ed Parrill A L, Jensen F, Jimena D Gorfinkiel, Keller A, Linert I, Marangos J P, Nikjoo H, Ryszka M, Samukawa S, Slaughter D S, Surko C M, Sylwia Ptasinska, Trevisan C S, Vizcaino V, Winstead C, Zecca A, Zubek M, Ómarsson B   +33 more
core   +1 more source

Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury

Advanced Science, EarlyView.
ABSTRACT Plastic food containers used in food delivery may pose underrecognized health risks by releasing micro‐ and nanoplastics (MNPs), especially when in contact with oil‐rich foods. Here, we show that cooking oil dramatically increased MNP release from polypropylene (PP) and polyethylene (PE)‐coated containers within 3 min of microwave heating ...
Ruwen Xie, Gulimire Yilihan, Qiong Chen, Dachuan Lin, Zhen Liu, Mengyi Yuan, Yujia Wang, Haoteng Xu, Weishang Zhou, Wanxin Gong, Yueer Li, Chen Peng, Tong Yang, Peng Gao, Qing Liu, Xin‐Hua Feng, Mu Xiao, Chao Jiang   +17 more
wiley   +1 more source

Quorum-sensing dysbiotic shifts in the HIV-infected oral metabiome. [PDF]

PLoS ONE, 2015
We implemented a Systems Biology approach using Correlation Difference Probability Network (CDPN) analysis to provide insights into the statistically significant functional differences between HIV-infected patients and uninfected individuals.
Robert E Brown, Mahmoud A Ghannoum, Pranab K Mukherjee, Patrick M Gillevet, Masoumeh Sikaroodi   +4 more
doaj   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Effects of Cyclic High Ambient Temperature on Muscle Imidazole Dipeptide Content in Broiler Chickens

The Journal of Poultry Science
Imidazole dipeptides possess important bioregulatory properties in animals. This study aimed to evaluate the effect of high ambient temperature on muscle imidazole dipeptides (carnosine, anserine, and balenine) in broiler chickens.
Ayumi Katafuchi, Mizuki Kamegawa, Serina Goto, Daichi Kuwahara, Yukiko Osawa, Saki Shimamoto, Shinya Ishihara, Akira Ohtsuka, Daichi Ijiri   +8 more
doaj   +1 more source

Homochirality in an early peptide world

, 2006
A recently proposed model of non-autocatalytic reactions in dipeptide reactions leading to spontaneous symmetry breaking and homochirality is examined. The model is governed by activation, polymerization, epimerization and depolymerization of amino acids.
Axel Brandenburg, Hare P.E., Harry J. Lehto, Kirsi M. Lehto   +3 more
core   +2 more sources

Enzymatic and chromatographic resolution procedures applied to the synthesis of the phosphoproline enantiomers [PDF]

, 2015
Financial support to this work was provided by Ministerio de Economía y Competitividad–FEDER (grants CTQ2011-24237,CTQ2013-44153-P, and CTQ2013-40855 ...
Arizpe, Alicia, Cativiela, Carlos, Gotor Fernández, Vicente, Gotor Santamaría, Vicente Miguel, Jiménez, Ana I., Pueyo, María J., Rodríguez Mata, María, Sayago García, Francisco Javier   +7 more
core   +2 more sources

The Ethnopharmacological, Phytochemical, and Pharmacological Review of Euryale ferox Salisb.: A Chinese Medicine Food Homology

Molecules, 2023
Euryale ferox Salisb. (prickly water lily) is the only extent of the genus Euryale that has been widely distributed in China, India, Korea, and Japan. The seeds of E.
Jiahui Jiang, Haiyan Ou, Ruiye Chen, Huiyun Lu, Longjian Zhou, Zhiyou Yang   +5 more
doaj   +1 more source