Results 71 to 80 of about 464,022 (216)

Energetics of Cyclic Dipeptide Crystal Packing and Solvation

Biophysical Journal, 1997
Calculations of the thermodynamics of transfer of the cyclic alanine-alanine (cAA) and glycine-glycine (cGG) dipeptides between the gas, water, and crystal phases were carried out using a combination of molecular mechanics, normal mode analysis, and continuum electrostatics. The experimental gas-to-water solvation free energy and the enthalpy of gas-to-
Brady, G.Patrick, Sharp, Kim A.
openaire   +2 more sources

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Proteo‐transcriptomic insights into the venom composition of the ectoparasitoid Eupelmus urozonus

Pest Management Science, EarlyView.
Integrated venom‐gland transcriptomics and venom proteomics of Eupelmus urozonus identified 316 venom proteins, including 75 secreted candidates, revealing diverse hydrolases, proteases/inhibitors and many uncharacterized effectors. Abstract BACKGROUND Ectoparasitoid venoms are ‘cocktails’ of bioactive molecules injected during oviposition to paralyze ...
Federica De Stefano, Carmen Scieuzo, Rosanna Salvia, Riccardo Moretti, Flora Cozzolino, Maria Monti, Heiko Vogel, Patrizia Falabella   +7 more
wiley   +1 more source

One‐Pot Fabrication of Pentapeptide Bio‐Aerogel via Direct Alcogelation

Small, EarlyView.
A minimal tachykinin‐inspired pentapeptide (TC‐1) self‐assembles in water and ethanol to form robust gels that can be dried in one pot to ultra‐porous aerogels using supercritical carbon dioxide. Solvent choice programs nanoscale packing and bulk mechanics producing lightweight monoliths with high porosity for biomaterials applications, verified by ...
Brody McDonald, Durga Dharmadana, Nevena Todorova, Boyin Liu, Shuaiyu Jiang, Ewan W. Blanch, Céline Valéry   +6 more
wiley   +1 more source

Integrative Bioinformatics, Experimental Validation, and Interpretable Machine Learning Reveal Oxyresveratrol‐Mediated Protection Against Cadmium‐Induced Lung Adenocarcinoma‐Related Transcriptional Dysregulation

Environmental Toxicology, EarlyView.
ABSTRACT Cadmium (Cd) is a toxic heavy metal strongly implicated in lung adenocarcinoma (LUAD) through mechanisms involving oxidative stress, epigenetic dysregulation, and chronic inflammation. This study aimed to identify Cd‐responsive genes associated with LUAD and to evaluate the protective effects of oxyresveratrol (O‐RES) against Cd‐induced ...
Murat Isıyel, Hamid Ceylan, Yeliz Demir
wiley   +1 more source

High-tolerance crystalline hydrogels formed from self-assembling cyclic dipeptide

Beilstein Journal of Nanotechnology, 2019
Peptide-based supramolecular hydrogels, as a new type of biological nanoarchitectonic structure, hold great promise for a wide range of biomedical and nanotechnological applications, such as tissue engineering, drug delivery, and electronic and photonic ...
Yongcai You, Ruirui Xing, Qianli Zou, Feng Shi, Xuehai Yan   +4 more
doaj   +1 more source

Crown-ether-modified cyclic dipeptides as supramolecular chiral catalysts

, 2017
With the objective to develop supramolecular catalysts for useful chemical transformations, we report here a rapid and efficient solid-phase synthesis of novel cyclic dipeptides (crown-CDPs) with a diversity of L-DOPA derived crown ether substituents and
Voyer, Normand, Bérubé, Christopher
core   +1 more source

Cyclic dipeptides: Biological activities and self-assembled materials

, 2020
Cyclic dipeptides (CDPs) are the smallest cyclic peptides containing 2,5-diketopiperazine rings. CDPs have advantages of structures and properties, including excellent hydrogen-bonding-forming ability (two hydrogen bonding acceptors and two hydrogen ...
Yan, Xuehai, Ruirui Xing, Kaili Zhao, Zhao, Kaili, Xuehai Yan, Xing, Ruirui   +5 more
core   +1 more source

Tree species identity is associated with rhizosphere microbiome assembly via root metabolite‐mediated feedbacks in subtropical forests

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract The rhizosphere microbiome is critical for forest ecological functions, yet the mechanisms through which tree species identity and neighbour tree interactions are associated with its assembly remain poorly understood.
Yuemei Zhang, Junchen Ye, Yao Kang, Yangchunzi Liao, Ziwen Jiao, Wenjing Meng, Lin Chang, Bing Liu, Yilin Li, Ziwen Gao, Ning Li, Hui Sun, Lin Huang   +12 more
wiley   +1 more source

Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament

Nature Communications
Cyclic dipeptides are produced by organisms across all domains of life, with many exhibiting anticancer and antimicrobial properties. Oxidations are often key to their biological activities, particularly C-C bond oxidation catalysed by tailoring enzymes ...
Emmajay Sutherland, Christopher J. Harding, Tancrède du Monceau de Bergendal, Gordon J. Florence, Katrin Ackermann, Bela E. Bode, Silvia Synowsky, Ramasubramanian Sundaramoorthy, Clarissa Melo Czekster   +8 more
doaj   +1 more source