Results 71 to 80 of about 4,865 (234)
Image5_C9orf72-Derived Proline:Arginine Poly-Dipeptides Modulate Cytoskeleton and Mechanical Stress Response.TIF [PDF]
, 2022 Proline:arginine (PR) poly-dipeptides from the GGGGCC repeat expansion in C9orf72 have cytotoxicity and bind intermediate filaments (IFs). However, it remains unknown how PR poly-dipeptides affect cytoskeletal organization and focal adhesion (FA ...
Masaya Matsubayashi (9030926) +12 more
core +1 more source
Molecules, 2023 Euryale ferox Salisb. (prickly water lily) is the only extent of the genus Euryale that has been widely distributed in China, India, Korea, and Japan. The seeds of E.
Jiahui Jiang +5 more
doaj +1 more source
Image1_C9orf72-Derived Proline:Arginine Poly-Dipeptides Modulate Cytoskeleton and Mechanical Stress Response.TIF [PDF]
, 2022 Proline:arginine (PR) poly-dipeptides from the GGGGCC repeat expansion in C9orf72 have cytotoxicity and bind intermediate filaments (IFs). However, it remains unknown how PR poly-dipeptides affect cytoskeletal organization and focal adhesion (FA ...
Masaya Matsubayashi (9030926) +12 more
core +1 more source
Cyclodipeptide oxidase is an enzyme filament
Nature CommunicationsModified cyclic dipeptides represent a widespread class of secondary metabolites with diverse pharmacological activities, including antibacterial, antifungal, and antitumor.
Michael P. Andreas, Tobias W. Giessen
doaj +1 more source
Efficient Microwave Assisted Syntheses of 2,5-Diketopiperazines in Aqueous Media
Molecules, 2009 Aqueous in situ one-pot N-Boc-deprotection-cyclization of Nα-Boc-dipeptidyl-tert-butyl and methyl esters under microwave irradiation afforded 2,5-diketopiperazines (DKPs) in excellent yields.
María Yolanda Rios +3 more
doaj +1 more source
Late‐Stage Functionalization of Peptides on the Solid Phase
Angewandte Chemie International Edition, EarlyView.Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner +2 more
wiley +1 more source
Structure-Based Exploration of Cyclic Dipeptide Chitinase Inhibitors [PDF]
Journal of Medicinal Chemistry, 2004 Family 18 chitinases play an essential role in a range of pathogens and pests. Several inhibitors are known, including the potent inhibitors argadin and allosamidin, and the structures of these in complex with chitinases have been elucidated. Recent structural analysis has revealed that CI-4 [cyclo-(L-Arg-D-Pro)] inhibits family 18 chitinases by ...
Houston, Douglas R. +5 more
openaire +3 more sources
Correlation of electronic structures of three cyclic dipeptides with their photoemission spectra [PDF]
, 2010 We have investigated the electronic structure of three cyclic dipeptides: cyclo (Glycyl-Glycyl) (cGG), cyclo(Leucyl-Prolyl) (cLP), and cyclo(Phenylalanyl-Prolyl) (cPP).
Vitaliy Feyer (1805521) +4 more
core +1 more source
Cyclic Dipeptides Produced by Marine Sponge-Associated Bacteria as Quorum Sensing Signals
Natural Product Communications, 2014 Four bacterial strains belonging to the genera Vibrio, Pseudoalteromonas and Photobacterium were isolated from the marine sponges Dysidea avara and Geodia cynodium . A Bacillus strain was isolated from Ircinia variabilis .
Gennaro Roberto Abbamondi +3 more
doaj +1 more source
Angewandte Chemie International Edition, EarlyView.An on‐resin dual‐modification strategy for peptides is presented, comprising S‐alkynylation of peptide thiosulfonates and regioselective iridium‐catalyzed azide–thioalkyne cycloaddition. This method reliably provides access to peptides with intricate non‐canonical modifications, being compatible with complex peptides, alkynes and azides.
Marius Werner +5 more
wiley +1 more source