Results 61 to 70 of about 464,022 (216)

A Green Protocol for the Deprotection of ortho‐Nitrobenzyl Esters and Ethers by UVA–LED Irradiation

Chemistry – A European Journal, EarlyView.
This study presents a green and efficient photochemical protocol for the deprotection of ortho‐nitrobenzyl esters or ethers under mild conditions, using UVA‐LED irradiation in methanol. The broad applicability of the protocol was validated in the synthesis of a cytosolic phospholipase A2 inhibitor. ABSTRACT The removal of protecting groups in synthetic
Despoina Poikilidou, Christiana Mantzourani, George Kokotos, Christoforos G. Kokotos   +3 more
wiley   +1 more source

The Ethnopharmacological, Phytochemical, and Pharmacological Review of Euryale ferox Salisb.: A Chinese Medicine Food Homology

Molecules, 2023
Euryale ferox Salisb. (prickly water lily) is the only extent of the genus Euryale that has been widely distributed in China, India, Korea, and Japan. The seeds of E.
Jiahui Jiang, Haiyan Ou, Ruiye Chen, Huiyun Lu, Longjian Zhou, Zhiyou Yang   +5 more
doaj   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Cyclodipeptide oxidase is an enzyme filament

Nature Communications
Modified cyclic dipeptides represent a widespread class of secondary metabolites with diverse pharmacological activities, including antibacterial, antifungal, and antitumor.
Michael P. Andreas, Tobias W. Giessen
doaj   +1 more source

Efficient Microwave Assisted Syntheses of 2,5-Diketopiperazines in Aqueous Media

Molecules, 2009
Aqueous in situ one-pot N-Boc-deprotection-cyclization of Nα-Boc-dipeptidyl-tert-butyl and methyl esters under microwave irradiation afforded 2,5-diketopiperazines (DKPs) in excellent yields.
María Yolanda Rios, Jaime Escalante, Horacio F. Olivo, Lemuel Pérez-Picaso   +3 more
doaj   +1 more source

Navigating the Radical Oxo‐Functionalization of Alkenes Toward Ketones

European Journal of Organic Chemistry, EarlyView.
Straightforward access to complex ketones in a single synthetic step: This Review surveys the latest advances in three‐component alkene 1,2‐oxo‐functionalizations. The opportunities unlocked by the so‐called single‐electron (1e–) logic, including access to a broad pool of radical precursors and carbonyl oxygen atom sources, are highlighted.
Mattia Lepori, Luigi Dolcini, Alexander Bell, Joshua P. Barham   +3 more
wiley   +1 more source

Synthesis and evaluation of eight-membered cyclic pseudo-dipeptides

, 2005
In the course of the development of calpain inhibitors, we report the synthesis of eight-membered cyclic pseudo dipeptides closely related to the known inhibitor SJA6017. The ring closure was effected by metathesis of the diallyl-substituted dipeptides 6
Coxon, J., Nikkel, J., Neffe, A., Jones, M., Miyamoto, S., Stuart, B., Brown, K., Abell, A.   +7 more
core   +1 more source

Specific peptide enrichment strategies for neuropsychiatric disorders: From material design to diagnostic applications

Interdisciplinary Medicine, EarlyView.
This review outlines specific peptide enrichment strategies, including metal, magnetic oxides, functional polymers, and antibody‐based approaches, and their mechanisms, highlighting applications in biomarker discovery for major neurological and psychiatric disorders.
Xue Zhang, Yejiao Shi, Minghui Guo, Yang Huang, Yirong Wang, Leping Huang, Helena S. Azevedo, Honggang Hu, Xin Dong   +8 more
wiley   +1 more source

Quantification of cyclic dipeptides from cultures of Lactobacillus brevis R2 Delta. by HRGC/MS using stable isotope dilution assay

, 2014
Lactic acid bacteria (LAB) play an important role as natural preservatives in fermented food and beverage systems, reducing the application of chemical additives.
Axel C, Waters DM, Czerny M, Arendt EK, Zannini E   +4 more
core   +2 more sources

Cyclic Dipeptides Produced by Marine Sponge-Associated Bacteria as Quorum Sensing Signals

Natural Product Communications, 2014
Four bacterial strains belonging to the genera Vibrio, Pseudoalteromonas and Photobacterium were isolated from the marine sponges Dysidea avara and Geodia cynodium . A Bacillus strain was isolated from Ircinia variabilis .
Gennaro Roberto Abbamondi, Salvatore De Rosa, Carmine Iodice, Giuseppina Tommonaro   +3 more
doaj   +1 more source