Results 121 to 130 of about 19,300 (178)

Updates on therapeutic targeting of diguanylate cyclase for addressing bacterial infections: A comprehensive review. [PDF]

World J Microbiol Biotechnol
Tawale RM, Ibrahim R, Aranjani JM.
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Cyclic GMP-dependent protein kinases in protozoa

Frontiers in Bioscience, 2005
PKG (cGMP-dependent protein kinase) is a major intracellular receptor for cGMP and mediates a range of downstream physiological functions. Although most studies have concentrated on mammalian isoforms, the advent of whole genome sequencing has lead to identification of orthologues from other diverse species.
David A, Baker, Wensheng, Deng
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Regulation of cardiac cyclic GMP-dependent protein kinase

Biochimica et Biophysica Acta (BBA) - General Subjects, 1981
Abstract An assay method based on the ability of high concentrations of Mg2+ to stimulate phosphorylation of histone in the presence of low concentrations of ATP was developed for the measurement of cyclic GMP-dependent protein kinase activity ratios (activity -cyclic GMP/activity + cyclic GMP).
T M, Lincoln, S L, Keely
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Cyclic GMP‐Dependent Protein Kinase Substrates in Rat Brain

Journal of Neurochemistry, 1995
Abstract: Cyclic GMP (cGMP)‐dependent protein kinase (PKG) has a limited substrate specificity, and only cerebellar G‐substrate has been demonstrated in brain. In view of the physiological importance of cGMP and PKG in the nervous system, it is important to identify endogenous PKG substrates in rat brain.
X, Wang, P J, Robinson
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Cyclic GMP-Dependent Protein Kinase and Smooth Muscle Relaxation

Journal of Cardiovascular Pharmacology, 1992
Cyclic guanosine monophosphate (cGMP)-dependent protein kinase has been cloned from bovine trachea. The isozymes I alpha and I beta, which differ only in their amino-terminal domains were expressed transiently in COS-7 cells. Both isozymes were activated by cGMP and cyclic adenosine monophosphate (cAMP).
W, Landgraf, P, Ruth, A, Keilbach, B, May, A, Welling, F, Hofmann   +5 more
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A role for cyclic-GMP dependent protein kinase in anoikis

Cellular Signalling, 2006
Anoikis is an essential process in which a loss of adhesion to the substratum alters intracellular signaling pathways that lead to apoptosis. Using phosphorylation of vasodilator stimulated phosphoprotein (VASP) as an indicator of cGMP-dependent protein kinase (PKG) activity in vivo, it was found that suspension of the colon epithelial cell line ...
Yali, Hou, Elsie, Wong, Jessica, Martin, Patricia V, Schoenlein, Wolfgang R, Dostmann, Darren D, Browning   +5 more
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Phosphorylation of Tyrosine Hydroxylase by Cyclic GMP‐Dependent Protein Kinase

Journal of Neurochemistry, 1987
Abstract: Tyrosine hydroxylase purified from rat pheochro‐mocytoma was phosphorylated and activated by purified cyclic GMP‐dependent protein kinase as well as by cyclic AMP‐dependent protein kinase catalytic subunit. The extent of activation was correlated with the degree of phosphate incorporated into the enzyme.
R, Roskoski, P R, Vulliet, D B, Glass
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Cyclic AMP-Dependent and Cyclic GMP-Dependent Protein Kinases of Nervous Tissue

1981
Publisher Summary This chapter focuses on cyclic AMP (cAMP)-dependent and cyclic GMP (cGMP) -dependent protein kinases of nervous tissue. Information about cAMP-dependent and cGMP-dependent protein kinases of brain has increased considerably over the last few years. It is now fairly well established that two types of cAMP-dependent protein kinase and
U, Walter, P, Greengard
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Molecular and Physiopathologic Aspects of Mammalian Cyclic GMP-Dependent Protein Kinase

Annual Review of Pharmacology and Toxicology, 1978
Following the initial discovery of adenosine 3',5'-monophosphate (cyclic AMP)­ dependent protein kinase (hereafter referred to as A-PK) in rabbit skeletal muscle (1), the cyclic AMP target enzyme was subsequently found to occur ubiquitously in mammalian (2) and nonmammalian (2-4) tissues. The molecular properties and biological roles of the enzyme have
J F, Kuo, M, Shoji, W N, Kuo
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