Nitric Oxide Regulates Cyclic GMP‐Dependent Protein Kinase Phosphorylation in Rat Brain [PDF]
Journal of Neurochemistry, 1998 Abstract: Nitric oxide (NO) acts via soluble guanylyl cyclase to increase cyclic GMP (cGMP), which can regulate various targets including protein kinases. Western blotting showed that type II cGMP‐dependent protein kinase (cGK II) is widely expressed in various brain regions, especially in the thalamus.
A E, El-Husseini +4 more
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Transcriptomic Studies Reveal that the Rhizobium leguminosarum Serine/Threonine Protein Phosphatase PssZ has a Role in the Synthesis of Cell-Surface Components, Nutrient Utilization, and Other Cellular Processes [PDF]
, 2019 Rhizobium leguminosarum bv. trifolii is a soil bacterium capable of establishing symbiotic associations with clover plants (Trifolium spp.). Surface polysaccharides, transport systems, and extracellular components synthesized by this bacterium are ...
Janczarek, Monika +2 more
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Cofactor Fingerprinting with STD NMR to Characterize Proteins of Unknown Function: Identification of a Rare cCMP Cofactor Preference [PDF]
, 2004 Proteomics efforts have created a need for better strategies to functionally categorize newly discovered proteins. To this end, we have employed saturation transfer difference NMR with pools of closely related cofactors, to determine cofactor preferences.
Sem, Daniel, Yao, Huili
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Compartmentalization of cyclic GMP-dependent protein kinase in formyl- peptide stimulated neutrophils [PDF]
Blood, 1990 Abstract The presence and physiologic role of cyclic GMP-dependent protein kinase (G-kinase) in human neutrophils was investigated by Western blot analysis and immunocytochemistry. Small quantities of G-kinase were found in the cytoskeletal-enriched fraction of neutrophil lysates as detected by Western blots using a polyclonal antibody ...
K B, Pryzwansky +3 more
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Two-component systems required for virulence in Pseudomonas aeruginosa [PDF]
, 2017 This is the author accepted manuscript. The final version is available from Oxford University Press via the DOI in this record.Pseudomonas aeruginosa is a versatile opportunistic pathogen capable of infecting a broad range of hosts, in addition to ...
Francis, VI, Porter, SL, Stevenson, EC
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Mechanisms involved in the remyelinating effect of sildenafil [PDF]
, 2018 Remyelination occurs in demyelinated lesions in multiple sclerosis (MS) and pharmacological treatments that enhance this process will critically impact the long term functional outcome in the disease.
Díaz-Lucena, Daniela +5 more
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Cyclic GMP‐Dependent Protein Kinase and Cellular Signaling in the Nervous System [PDF]
Journal of Neurochemistry, 1997 Abstract: Nitric oxide (NO) and natriuretic peptide hormones play key roles in a surprising number of neuronal functions, including learning and memory. Most data suggest that they exert converging actions by elevation of intracellular cyclic GMP (cGMP) levels through activation of soluble and particulate guanylyl cyclases.
X, Wang, P J, Robinson
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Cyclic AMP signalling in pancreatic islets [PDF]
, 2010 Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Furman, Brian +2 more
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Regulation of Sensory Neuron Precursor Proliferation by Cyclic GMP‐Dependent Protein Kinase [PDF]
Journal of Neurochemistry, 1998 Abstract: Cyclic GMP (cGMP) is a molecular messenger involved in diverse cellular processes. Recently, cGMP‐dependent protein kinase (cGK) type II was determined to be a regulator of endochondral ossification and bone growth, identifying a role for cGMP in the regulation of cellular proliferation.
B L, Firestein, D S, Bredt
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