Results 121 to 130 of about 36,202 (265)

Cyclic GMP-AMP synthase deficiency predisposes the liver to alcohol-induced cell death and ER stress. [PDF]

Hepatol Commun
Babuta M, Datta AA, de Carvalho Ribeiro M, Santos BACD, Morel C, Copeland C, Ortega-Ribera M, Mehta J, Calenda C, Wang Y, Remotti V, Brezani V, Patel A, Hawryluk D, Szabo G.   +14 more
europepmc   +1 more source

High-Intensity Interval Training Ameliorates High-Fat Diet-Induced Metabolic Disorders via the Cyclic GMP-AMP Synthase-Stimulator of Interferon Gene Signaling Pathway. [PDF]

Int J Mol Sci, 2023
Hu Z, Li X, Yang Y, Zhang Z, Ding S.
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Pathophysiological and therapeutic implications of C-type natriuretic peptide/cyclic GMP signaling in pulmonary fibrosis. [PDF]

JCI Insight
Weyer R, Völker K, Potapenko T, Krebes L, Abeßer M, Friedrich AL, Lessmann E, Khadim A, Ruppert C, El Agha E, Sheta D, Beilhack A, Santi DV, Schneider EL, Kuhn M, Dabral S.   +15 more
europepmc   +1 more source

Receptor Guanylyl Cyclase C and Cyclic GMP in Health and Disease: Perspectives and Therapeutic Opportunities. [PDF]

Front Endocrinol (Lausanne), 2022
Prasad H, Mathew JKK, Visweswariah SS.
europepmc   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source

Bridging innate immunity and iron-dependent death: the interplay between cyclic GMP-AMP synthase-stimulator of interferon genes nexus and ferroptosis in cancer and inflammation. [PDF]

Front Cell Dev Biol
Chen XX, Hou YQ, Chen XX, Zhou Q, Wang X.   +4 more
europepmc   +1 more source

Cyclic GMP in Liver Cirrhosis-Role in Pathophysiology of Portal Hypertension and Therapeutic Implications. [PDF]

Int J Mol Sci, 2021
Kreisel W, Lazaro A, Trebicka J, Grosse Perdekamp M, Schmitt-Graeff A, Deibert P.   +5 more
europepmc   +1 more source

Intratumoral bacteria engineered for tumor therapy

Interdisciplinary Medicine, EarlyView.
This article comprehensively reviews engineered intratumoral bacteria used in tumor therapy. The concept development, characteristics, and engineering methods of intratumoral bacteria are summarized. The mechanisms and the translational significance by which engineered intratumoral bacteria interfere with tumor progression are discussed and highlighted.
Huajie Zhang, Zelin Chen, Zeyu Yao, Sishi Luo, Cheng Luo, Rui Yang, Hao Fu, Songyin Huang   +7 more
wiley   +1 more source

An acyclic nucleoside phosphonate effectively blocks the egress of the malaria parasite by inhibiting the synthesis of cyclic GMP. [PDF]

Sci Adv
Ali M, Dura R, Guery MA, Colard-Itté E, Cheviet T, Robresco L, Berry L, Lionne C, Lavazec C, Claessens A, Peyrottes S, Wengelnik K, Wein S, Cerdan R.   +13 more
europepmc   +1 more source