Bi-modal distribution of the second messenger c-di-GMP controls cell fate and asymmetry during the caulobacter cell cycle [PDF]
Many bacteria mediate important life-style decisions by varying levels of the second messenger c-di-GMP. Behavioral transitions result from the coordination of complex cellular processes such as motility, surface adherence or the production of virulence ...
Abel, Sören +27 more
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The STING (stimulator of interferon genes) protein can bind cyclic dinucleotides to activate the production of type I interferons and inflammatory cytokines.
Guanghui Yi +5 more
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Folding of the transcription factor Brinker and interactions of the bacterial second messenger c-di-GMP studied by NMR [PDF]
Nuclear magnetic resonance (NMR) spectroscopy is a technique, which allows the non-invasive investigation of structures, dynamics and interactions of biomolecules.
Gentner, Martin
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Digital image processing of optical density wave propagation in Dictyostelium discoideum and analysis of the effects of caffeine and ammonia [PDF]
Waves of chemotactic movement during the early phase of aggregation in Dictyostelium discoideum were analyzed by digital image processing in a manner that immediately shows the following parameters: wave propagation velocity, period length, wave ...
Siegert, Florian, Weijer, Cornelis J.
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Guanylin peptides: cyclic GMP signaling mechanisms
Guanylate cyclases (GC) serve in two different signaling pathways involving cytosolic and membrane enzymes. Membrane GCs are receptors for guanylin and atriopeptin peptides, two families of cGMP-regulating peptides.
L.R. Forte +3 more
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Nucleotides as Bacterial Second Messengers
In addition to comprising monomers of nucleic acids, nucleotides have signaling functions and act as second messengers in both prokaryotic and eukaryotic cells. The most common example is cyclic AMP (cAMP).
Mario E. Cancino-Diaz +3 more
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The regulation of alginate biosynthesis via cyclic di-GMP signaling
Bacterial alginates are anionic exopolysaccharides, which are produced by Pseudomonas and Azotobacter species. Bacterial cells embedded in extracellular polymeric substances such as alginates have a survival advantage as they are protected against ...
Rehm, BHA, Moradali, MF
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Bacterial cyclic diguanylate signaling networks sense temperature
Many bacteria use the second messenger cyclic diguanylate (c-di-GMP) to control motility, biofilm production and virulence. Here, the authors identify a thermosensitive enzyme that synthesizes c-di-GMP and modulates temperature-dependent motility ...
Henrik Almblad +29 more
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Activation and polar sequestration of PopA, a c-di-GMP effector protein involved in Caulobacter crescentus cell cycle control [PDF]
When Caulobacter crescentus enters S-phase the replication initiation inhibitor CtrA dynamically positions to the old cell pole to be degraded by the polar ClpXP protease.
Ebbensgaard, Anna Elisabeth +7 more
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Multilimbed membrane guanylate cyclase signaling system, evolutionary ladder
One monumental discovery in the field of cell biology is the establishment of the membrane guanylate cyclase signal transduction system. Decoding its fundamental, molecular, biochemical, and genetic features revolutionized the processes of developing ...
Teresa Duda, Rameshwar K. Sharma
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