Results 61 to 70 of about 43,561 (311)
Extraction and Quantification of Cyclic Di-GMP from Pseudomonas aeruginosa
Bio-Protocol, 2013 Cyclic di-GMP (c-di-GMP) has emerged as an important intracellular signaling molecule, controlling the transitions between planktonic (free-living) and sessile lifestyles, biofilm formation, and virulence in a wide variety of microorganisms.
Ankita Roy, Olga Petrova, Karin Sauer
doaj +1 more source
The role of cGMP signalling in regulating life cycle progression of Plasmodium. [PDF]
, 2012 The 3'-5'-cyclic guanosine monophosphate (cGMP)-dependent protein kinase (PKG) is the main mediator of cGMP signalling in the malaria parasite. This article reviews the role of PKG in Plasmodium falciparum during gametogenesis and blood stage schizont ...
Baker, David A +2 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
ROS-GC interlocked Ca2+-sensor S100B protein signaling in cone photoreceptors: Review
Frontiers in Molecular Neuroscience, 2014 Photoreceptor rod outer segment membrane guanylate cyclase (ROS-GC) is central to visual transduction; it generates cyclic GMP, the second messenger of the photon signal.
Rameshwar K Sharma +3 more
doaj +1 more source
Screening for Diguanylate Cyclase (DGC) Inhibitors Mitigating Bacterial Biofilm Formation
Frontiers in Chemistry, 2020 The majority of bacteria in the natural environment organize themselves into communal biofilms. Biofilm formation benefits bacteria conferring resistance to harmful molecules (e.g., antibiotics, disinfectants, and host immune factors) and coordinating ...
Kyu Hong Cho +2 more
doaj +1 more source
Chemiluminescent Biosensors for Detection of Second Messenger Cyclic di-GMP
, 2018 Bacteria colonize highly diverse and complex environments, from gastrointestinal tracts to soil and plant surfaces. This colonization process is controlled in part by the intracellular signal cyclic di-GMP, which regulates bacterial motility and biofilm ...
Dippel, Andrew B +14 more
core +1 more source
Application of Ibuprofen Sodium Dihydrate for Thermochemical Energy Storage
Advanced Functional Materials, EarlyView.Ibuprofen sodium dihydrate is introduced as a durable organic salt hydrate for low‐temperature thermochemical energy storage, operating within 60°C–110°C with high energy density. At the material level, it delivers ∼99.9% cycling efficiency over 150 cycles without deliquescence, enabled by a dual energy‐storage mechanism coupling dehydration and phase ...
Kavin Chakravarthy Thangaraj +10 more
wiley +1 more source
Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review
Advanced Healthcare Materials, EarlyView.Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami +4 more
wiley +1 more source
Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies
Advanced Healthcare Materials, EarlyView.Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best +5 more
wiley +1 more source
Cell ReportsSummary: It was previously demonstrated that intestinal pathogens have evolved different mechanisms to enhance their infection and colonization in the intestines of hosts.
Mingfang Wang +7 more
doaj +1 more source