Results 1 to 10 of about 61,887 (296)

Regulation of Biofilm Exopolysaccharide Production by Cyclic Di-Guanosine Monophosphate [PDF]

Frontiers in Microbiology, 2021
Many bacterial species in nature possess the ability to transition into a sessile lifestyle and aggregate into cohesive colonies, known as biofilms.
Myles B. Poulin, Laura L. Kuperman
doaj   +4 more sources

Improvement of Chediak-Higashi leukocyte function by cyclic guanosine monophosphate [PDF]

Blood, 1977
Abstract The addition of cholinergic agents and cyclic 3′5′-guanosine monophosphate (cGMP) to polymorphonuclear leukocytes in vitro from a patient with Chediak-Higashi syndrome corrected the impaired release of the lysosomal enzyme, beta-glucuronidase, to normal. Coinciding with the improvement in degranulation, the bactericidal capacity
LA Boxer, M Rister, JM Allen, RL Baehner
semanticscholar   +6 more sources

Cyclic Guanosine Monophosphate Modulation and Blood Pressure [PDF]

Hypertension, 2014
See related article, pp 1241–1247 Few intracellular second messengers received more attention in cardiovascular basic and clinical research than cyclic GMP (cGMP). Guanylyl cyclases produce cGMP from its precursor molecule, guanosine triphosphate.
J. Jordan
openaire   +4 more sources

Cyclic guanosine monophosphate as a mediator of vasodilation. [PDF]

Journal of Clinical Investigation, 1986
Although cyclic guanosine monophosphate (GMP)' was first described in biological samples more than two decades ago, its role in some physiological processes has only become apparent in the past few years (see references 1-4).
F. Murad
openaire   +4 more sources

Saxagliptin and Tadalafil Differentially Alter Cyclic Guanosine Monophosphate (cGMP) Signaling and Left Ventricular Function in Aortic‐Banded Mini‐Swine

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundCyclic guanosine monophosphate‐protein kinase G‐phosphodiesterase 5 signaling may be disturbed in heart failure (HF) with preserved ejection fraction, contributing to cardiac remodeling and dysfunction.
Jessica A. Hiemstra, Dong I. Lee, Khalid Chakir, Manuel Gutiérrez‐Aguilar, Kurt D. Marshall, Pamela J. Zgoda, Noelany Cruz Rivera, Daniel G. Dozier, Brian S. Ferguson, Denise M. Heublein, John C. Burnett, Carolin Scherf, Jan R. Ivey, Gianmaria Minervini, Kerry S. McDonald, Christopher P. Baines, Maike Krenz, Timothy L. Domeier, Craig A. Emter   +18 more
doaj   +2 more sources

Immunohistochemical studies of cyclic guanosine monophosphate and nuclear function. [PDF]

Journal of Clinical Investigation, 1980
In previous immunohistochemical studies, it has been found that all nuclei contain cyclic (c)GMP, which occurs in discrete aggregates and in the nucleolus. We have studied the nature of the cGMP aggregates in isolated mouse fetal nuclei using a specific immunofluorescent technique.
EDWARD M. ROSENBERG, James G. Conway, Steven M. Tucci, E W Doucet   +3 more
openalex   +3 more sources

Cyclic nucleotide signalling in malaria parasites [PDF]

Open Biology, 2017
The cyclic nucleotides 3′, 5′-cyclic adenosine monophosphate (cAMP) and 3′, 5′-cyclic guanosine monophosphate (cGMP) are intracellular messengers found in most animal cell types.
David A. Baker, Laura G. Drought, Christian Flueck, Stephanie D. Nofal, Avnish Patel, Maria Penzo, Eloise M. Walker   +6 more
doaj   +4 more sources

Chemo- and Thermosensory Responsiveness of Grueneberg Ganglion Neurons Relies on Cyclic Guanosine Monophosphate Signaling Elements [PDF]

Neurosignals, 2011
Neurons of the Grueneberg ganglion (GG) in the anterior nasal region of mouse pups respond to cool temperatures and to a small set of odorants. While the thermosensory reactivity appears to be mediated by elements of a cyclic guanosine monophosphate ...
Katharina Mamasuew, Nina Hofmann, Verena K. Kretzschmann, M. Biel, Ruey-Bing Yang, H. Breer, Joerg Fleischer   +6 more
semanticscholar   +4 more sources

Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensis [PDF]

Memorias do Instituto Oswaldo Cruz, 2003
Although there are some data concerning the nitric oxide and the cyclic 3'-5'guanosine monophosphate (cGMP) signaling pathway in trypanosomatids, there is no report about the cGMP-dependent enzymatic activity identification.
LF Géigel, LL Leon
doaj   +2 more sources

Cyclic Guanosine Monophosphate Signaling and Phosphodiesterase-5 Inhibitors in Cardioprotection

Journal of the American College of Cardiology, 2012
Cyclic guanosine monophosphate (cGMP) is an important intracellular second messenger that mediates multiple tissue and cellular responses. The cGMP pathway is a key element in the pathophysiology of the heart and its modulation by drugs such as phosphodiesterase (PDE)-5 inhibitors and guanylate cyclase activators may represent a promising therapeutic ...
Anindita Das, Fadi N Salloum, Rakesh C. Kukreja   +2 more
openaire   +4 more sources