Results 191 to 200 of about 38,088 (227)

Nitric oxide and cyclic guanosine monophosphate signaling in the eye

Canadian Journal of Ophthalmology, 2008
This brief review describes the components and pathways utilized in nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) signaling. Since the discovery of the effects of NO and cGMP on smooth muscle relaxation about 30 years ago, the field has expanded in many directions such that many, but not all, biochemical and biological effects seem to be ...
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Cyclic Guanosine Monophosphate Role in Human Carcinoma Pathogenesis

Nucleosides, Nucleotides and Nucleic Acids, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Di Nicola Maurizio, Santoleri Fiorenzo, Soscia Stefano, Fioroni Massimiliano, Rubini Corrado, PIATTELLI, Adriano, SPOTO, Giuseppe   +6 more
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Cyclic adenosine monophosphate and cyclic guanosine monophosphate variations during isometric tetanus in frog sartorius muscle

Canadian Journal of Physiology and Pharmacology, 1982
Tetanic stimulation at different temperatures (5 and 20 °C) of the frog sartorius muscle results in an increase of cyclic guanosine monophosphate (cGMP) directly correlated to the tension developed. Cyclic adenosine monophosphate (cAMP) levels change differently for different temperature values.
Fanò G., Menchetti G., Della Torre G., Volpi L., SECCA, Teresa, ORLACCHIO, Aldo   +5 more
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Antagonists of excitatory amino acids and cyclic guanosine monophosphate in cerebellum

Neuropharmacology, 1982
The excitatory amino acid analogues kainate, quisqualate, domoic acid, 4-fluoroglutamate, homocysteic acid and N-methylaspartate as well as the tremor-inducing drugs harmaline and oxotremorine all induced significant elevations in cyclic guanosine monophosphate (cGMP) levels in the cerebellum in vivo. The putative antagonists of excitatory amino acids,
P L, Wood, J W, Richard, C, Pilapil, N P, Nair   +3 more
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Cyclic guanosine-3??5?-monophosphate induced diuresis in rats

Naunyn-Schmiedeberg's Archives of Pharmacology, 1974
In excretion studies in dogs it was found that cyclic guanosine-3′∶5′-monophosphate (cGMP) was eliminated by glomerular filtration only. If there is any permeability of the tubule cells to exogenous cGMP, it must be very low. cGMP (5×10−5 moles) injected into the thoracic aorta of rats induced an increase of the renal electrolyte excretion.
H. Osswald, O. Jacobs
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Stimulation of polypeptide synthesis by cyclic 3′-5′-guanosine monophosphate

Archives of Biochemistry and Biophysics, 1973
Abstract 3′-5′-Cyclic GMP was found to stimulate polyphenylalanine synthesis in a cell-free system derived from rat liver. The effect of cyclic GMP is detected either in the presence or absence of GTP and appears quite specific since it is not produced by other cyclic nucleotides.
S, Varrone, R, Di Lauro, V, Macchia
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Dibenzoquinazoline diones as antihypertensive cyclic guanosine monophosphate phosphodiesterase inhibitors

Biochemical Pharmacology, 1987
The discovery and structure-activity of a new class of renal artery phosphodiesterase inhibitors is reported, some of which are highly selective for the guanosine cyclic 3',5'-monophosphate phosphodiesterase. One of these compounds, 5,6-dihydro-8,9,11,12-tetramethoxy-1,3-dioxo-1H-benz[f]- isoquino [8,1,2- hij]quinazoline-2(3H)-carboxylic acid, ethyl ...
R F, Booth, S P, Buckham, D O, Lunt, P W, Manley, R A, Porter   +4 more
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A possible role for cyclic guanosine monophosphate in the rat pineal gland

Neuroscience Letters, 1990
Adrenergic stimulation of pinealocytes induces an increase of both cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). However, for cGMP no biological effects have been demonstrated so far. Therefore we tested the effects of the analog 8-bromo-cGMP on synaptic ribbon numbers and on melatonin synthesis as reflected by N ...
A, Seidel, A, Kantarjian, L, Vollrath
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Cyclic guanosine monophosphate in heart failure

The Lancet, 1993
Johannes Mair, Gabi Jakob, Max Pichler, Franz Dienstl, Bernd Puschendorf   +4 more
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The Role of Cyclic Guanosine Monophosphate Signaling in Biomechanics

Die Dissertation ist gesperrt bis zum 12. Dezember 2026 !
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