Results 31 to 40 of about 1,209,775 (291)

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Thermal effect of plastic dissipation at the crack tip on the stress intensity factor under cyclic loading [PDF]

, 2011
The authors acknowledge Arts et Métiers ParisTech and Fondation Arts et Métiers for the financial support of Paul C. Paris’ stay at LAMEFIP in 2009. The encouragement of Prof. Ivan Iordanoff, Director of LAMEFIP, is acknowledged with thanks.
PARIS, Paul C., T. Palin-Luc, PARIS, Paul Croce, PALIN-LUC, Thierry, RANC, Nicolas, P.C. Paris, PALIN LUC, Thierry, N. Ranc, Paris, Paul   +8 more
core   +1 more source

Numerical investigation of CFRP strengthened RHS members under cyclic loading [PDF]

, 2020
Rectangular hollow section (RHS) steel members are commonly utilized in various mechanical and civil engineering applications, but they have shown to be quite vulnerable under cyclic loading. In both onshore and offshore infrastructure, steel members can
Tafsirojjaman, T., Zhao, X. L., Fawzia, Sabrina, Thambiratnam, David   +3 more
core   +1 more source

Coupling effects of cyclic confining pressure and loading frequency on deformation behavior of saturated soft clay under intermittent cyclic loading

Yantu gongcheng xuebao
After the train passes away, the subgrade soils undergo cyclic loading and intermittent periods. The existence of the intermittent period can also affect the mechanical properties of soil.
HUANG Juehao 1, 2 , ZHONG Yu 3, WU Jiaming 4, MENG Chao 5, 1, CHEN Jian 1, 2, FU Xiaodong 1, 2
doaj   +1 more source

Mechanical Behavior and Damage Evolution for Granite Subjected to Cyclic Loading

Advances in Materials Science and Engineering, 2018
This paper focuses on the mechanical behavior and damage evolution of Huashan granite subjected to cyclic loading. Four levels of confining pressure (0, 15, 25, and 35 MPa) were applied during cyclic axial loading by using a Rock Test System (MTS815 ...
Zhiliang Wang, Jikang Yao, Nuocheng Tian, Jingbin Zheng, Peng Gao   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

On the ratchet analysis of a cracked welded pipe [PDF]

, 2011
This paper presents the ratchet limit analysis of a pipe with a symmetric crack in a mismatched weld by using the extended Linear Matching Method (LMM). Two loading conditions are considered: i) a cyclic temperature load and a constant internal pressure;
Ure, James Michael, James Ure, Haofeng Chen, Chen, Haofeng, Li, Tianbai, Tianbai Li, Weihang Chen, Chen, Weihang   +7 more
core   +5 more sources