Results 41 to 50 of about 124,896 (264)

Deformation theory and energy mechanism of cyclic dynamic mechanical damage for granite in the diversion tunnel under cyclic loading-unloading

iScience
Summary: The diversion tunnel is frequently subjected to cyclic dynamic loads during blasting and mechanical excavation. To explore the theory and mechanism of cyclic dynamic mechanical damage for granite in a diversion tunnel under cyclic loading ...
Rongzhou Yang, Ying Xu
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Horizontal Cyclic Bearing Characteristics of Bucket Foundation in Sand for Offshore Wind Turbines

Energies
During the service period, the offshore wind turbine foundation mainly bears the wind load from the upper structure and the periodic loads such as wave load and sea currents from the lower structure. Long-term cyclic loads have an important impact on the
Hanbo Zhai, Puyang Zhang, Junqi Ren
doaj   +1 more source

Effects of cyclic loading on soil-geogrid interaction characteristics [PDF]

E3S Web of Conferences
The benefits of geosynthetic-reinforced soil systems over conventional earth-retaining structures are now well established. These reinforced systems are often subjected not only to static loads, but also to seismic and/or traffic loads, in which case the
Ferreira Fernanda B., Vieira Castorina S., Lopes Maria de Lurdes, Ferreira Pedro G.   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Anisotropic Mechanical Properties and Fracture Mechanism of Transversely Isotropic Rocks under Uniaxial Cyclic Loading

Applied Sciences
Transversely isotropic rocks, which are special anisotropic materials, are widely encountered in civil, mining, petroleum, geothermal, and radioactive waste-disposal engineering. Rock is frequently subject to cyclic loads resulting from natural and human-
Kaihui Li, Guangzhen Du, Jiangteng Li, Dongya Han, Yan Wang   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

EBSD characterization of martensitic transformation and texture evolution in lean duplex stainless steel under uniaxial loading

Journal of Materials Research and Technology
In this work, EBSD technique was applied to investigate the martensitic transformation characteristics and texture evolution laws in a lean duplex stainless steel (present LDX) along several uniaxial loading paths (i.e., tension, compression, cyclic ...
Shuling Guo, Zhenduo Sun, Na Li, Miao Jin, Lei Chen, Shuo Hao   +5 more
doaj   +1 more source