Results 41 to 50 of about 1,209,775 (291)

Post-Cyclic Drained Shear Behaviour of Fujian Sand under Various Loading Conditions

Journal of Marine Science and Engineering, 2022
In offshore engineering, the sand beneath an embankment may be subjected to traffic loads, resulting in a series of engineering issues. The behaviour of the sand beneath the embankment may change under a long-term traffic load. A series of drained cyclic
Ying Liu, Zhixuan Liang, Zhiyong Liu, Guiping Nie   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Bearing Performance of a Helical Pile for Offshore Photovoltaic under Horizontal Cyclic Loading

Journal of Marine Science and Engineering
For an offshore photovoltaic helical pile foundation, significant horizontal cyclic loading is imposed by wind and waves. To study a fixed offshore PV helical pile’s horizontal cyclic bearing performance, a numerical model of the helical pile under ...
Xinfu Cong, Zhe Li, Zhonghai An, Jiangxue Liu, Yanqing Han   +4 more
doaj   +1 more source

Coupling effects of bidirectional cyclic loading and loading frequency on pore water pressure of saturated soft clay

Yantu gongcheng xuebao, 2017
A series of undrained cyclic tests with variable confining pressures are conducted on Ningbo saturated soft clay by using the GDS cyclic triaxial system. In this study, the coupling effects of cyclic deviatoric stress and cyclic confining pressure on the
HUANG Jue-hao 1, 2, CHEN Jian 1, 2, KE Wen-hui 3, ZHONG Yu 4, QIU Yue-feng 1, 2
doaj   +1 more source

Mechanical properties and energy evolution characteristics of borehole-containing specimens under disturbances of cyclic incremental stress with different lower limits

Journal of Materials Research and Technology, 2023
Drilling gas drainage boreholes in coal mines is a major measure to prevent gas disasters in coal mines. However, coal mining disruptions can affect the stability and shape of gas drainage boreholes.
Xiaoyan Sun, Zihan Chen, Quanle Zou
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

CYCLIC PRESSUREMETER LOADING AND LIQUEFACTION PROPERTIES OF SANDS

SOILS AND FOUNDATIONS, 2003
Based on a series of cyclic cavity expansion tests carried out on a thick hollow cylinder apparatus (HCC) and on mini-pressuremeter tests performed in a calibration chamber, a method is proposed to establish a reliable correlation between the result of a "reference" cyclic expansion test carried out in a sand, in terms of cavity volume accumulation ...
Dupla, Jean Claude, Canou, Jean
openaire   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Experimental study on deformation behaviors of saturated soft clay under intermittent cyclic loading with various drained conditions

Yantu gongcheng xuebao
In the previous studies, the cyclic triaxial tests under intermittent cyclic loading are used to study the deformation characteristics of soft clay under traffic loads. Both confining pressure and deviator stress vary cyclically in the stress field under
HUANG Juehao 1, 2, XU Linfeng 3, 1, LU Yuan 5, YAN Wenlong 4, 1, CHEN Jian 1, 2, FU Xiaodong 1, 2
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source