Results 61 to 70 of about 375,823 (310)
Applied SciencesTransversely isotropic rocks, which are special anisotropic materials, are widely encountered in civil, mining, petroleum, geothermal, and radioactive waste-disposal engineering. Rock is frequently subject to cyclic loads resulting from natural and human-
Kaihui Li +4 more
doaj +1 more source
Effects of cyclic loading on soil-geogrid interaction characteristics [PDF]
E3S Web of ConferencesThe benefits of geosynthetic-reinforced soil systems over conventional earth-retaining structures are now well established. These reinforced systems are often subjected not only to static loads, but also to seismic and/or traffic loads, in which case the
Ferreira Fernanda B. +3 more
doaj +1 more source
Precoded FIR and Redundant V-BLAST Systems for Frequency-Selective MIMO Channels [PDF]
, 2007 The vertical Bell labs layered space-time (V-BLAST) system is a multi-input multioutput (MIMO) system designed to achieve good multiplexing gain.
Chen, Chun-yang, Vaidyanathan, P. P.
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Journal of Materials Research and TechnologyIn this work, EBSD technique was applied to investigate the martensitic transformation characteristics and texture evolution laws in a lean duplex stainless steel (present LDX) along several uniaxial loading paths (i.e., tension, compression, cyclic ...
Shuling Guo +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Experimental study of strain accumulation of silica sand in a cyclic triaxial test [PDF]
, 2014 The experimental and phenomenological investigation of the elasto-plastic long-term behaviour of soils under dynamic loading is important for the development of risk analysis tools and numerical accumulation models for settlement prediction.
Benoot, Jelle +2 more
core
Cyclic J-integral using the linear matching method [PDF]
, 2013 The extended version of the latest Linear Matching Method (LMM) has the capability to evaluate the stable cyclic response, which produces cyclic stresses, residual stresses and plastic strain ranges for the low cycle fatigue assessment with cyclic load ...
Chen, Haofeng, Chen, Weihang
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source