Results 71 to 80 of about 375,823 (310)
Dissociating stable nitrogen molecules under mild conditions by cyclic strain engineering [PDF]
, 2019 All quiet on the nitrogen front. The dissociation of stable diatomic nitrogen molecules (N-2) is one of the most challenging tasks in the scientific community and currently requires both high pressure and high temperature.
Baek, Jong-Beom +11 more
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Sports Medicine, Arthroscopy, Rehabilitation, Therapy & Technology, 2012 Purpose The purpose of this study was to compare the anterior tibial translation (ATT) of the anterior cruciate ligament (ACL) reconstructed-knee between single-bundle and double-bundle ACL reconstruction under cyclic loading.
Nohmi Shuya +5 more
doaj +1 more source
Monopiles subjected to uni- and multi-lateral cyclic loading [PDF]
, 2017 Offshore wind turbines are subjected to significant environmental loads from a combination of current, wind and wave action. Under such conditions, the directions of these environmental loads vary over the service life of the structure and therefore the ...
Arthur, Iain +9 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Heterogeneous relaxation dynamics in amorphous materials under cyclic loading [PDF]
, 2013 Molecular dynamics simulations are performed to investigate heterogeneous dynamics in amorphous glassy materials under oscillatory shear strain. We consider three-dimensional binary Lennard-Jones mixture well below the glass transition temperature.
Priezjev, Nikolai V.
core +3 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Effects of loading frequency on cyclic parameters of unsaturated Zenoz kaolin
E3S Web of Conferences, 2016 According to the considerable effects of the loading frequency on the cyclic behaviour of the soils and lack of the sufficient and precise data in this field for the unsaturated soils, more attention needs to be paid to the experimental investigations in
Mojezi Mohsen +2 more
doaj +1 more source
PLoS ONE, 2020 Tendon elongation after Achilles tendon (AT) repair is associated with the clinical outcome. Reliable suture techniques are essential to reduce gap formations and to allow early mobilization.
Stephan Frosch +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source