Results 91 to 100 of about 375,823 (310)

Hydraulic servo system increases accuracy in fatigue testing [PDF]

open access: yes, 1967
Hydraulic servo system increases accuracy in applying fatigue loading to a specimen under test. An error sensing electronic control loop, coupled to the hydraulic proportional closed loop cyclic force generator, provides an accurately controlled peak ...
Dixon, G. V., Kibler, K. S.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Analysis of permeability evolution law of gas-bearing coal under cyclic loading condition

open access: yesMeitan kexue jishu
In order to explore the permeability evolution law of gas-bearing coal under different cyclic loading and unloading conditions, raw coal samples were taken as the research object, and cyclic loading-unloading experiments of gas-bearing coal were designed
Dengke WANG   +8 more
doaj   +1 more source

Life prediction modeling based on strainrange partitioning [PDF]

open access: yes
Strainrange partitioning (SRP) is an integrated low-cycle-fatigue life predicting system. It was created specifically for calculating cyclic crack initiation life under severe high-temperature fatigue conditions.
Halford, Gary R.
core   +1 more source

Creep fatigue life prediction for engine hot section materials (isotropic): Two year update [PDF]

open access: yes, 1984
Requirements for increased durability of gas turbine hot section components have placed a greater degree of importance on accurate structural analysis and life prediction.
Moreno, V.
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

A New Method for Predicting Dynamic Pile Head Stiffness Considering Pile–Soil Relative Stiffness Under Long-Term Cyclic Loading Conditions

open access: yesBuildings
Under long-term horizontal cyclic loading, the evolution characteristics of the loading and unloading stiffness of piles are an important representation of pile–soil interaction.
Jie Chen   +5 more
doaj   +1 more source

Effect of Cyclic Loading on the Elasticity of Beech Solid and Laminated Wood

open access: yesBioResources, 2014
This article deals with the determination of the cyclic loading effect on the elastic modulus (Em) of beech solid and laminated wood at various thicknesses while bent in the radial direction.
Milan Gaff, Jozef Gáborík
doaj   +1 more source

Linear matching method for design limits in plasticity [PDF]

open access: yes, 2010
In this paper a state-of-the-art numerical method is discussed for the evaluation of the shakedown and ratchet limits for an elastic-perfectly plastic body subjected to cyclic thermal and mechanical load history. The limit load or collapse load, i.e. the
Chen, Haofeng
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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