Results 181 to 190 of about 44,336 (211)

Cyclic Nucleotide Phosphodiesterases

2007
Cyclic nucleotide phosphodiesterases (PDEs) are a family of enzymes that function to terminate the action of the hormone …
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Cyclic nucleotides and cyclic nucleotide phosphodiesterase during development of Polysphondylium violaceum

Experimental Cell Research, 1979
Abstract Polysphondylium violaceum is shown to produce and excrete cyclic nucleotides and to produce a cell-associated cyclic nucleotide phosphodiesterase(s). The amount of adenosine 3′,5′-cyclic monophosphate (cAMP) excreted by the amebae reaches a maximum during development when aggregation centers are just forming and then falls off rapidly ...
M H, Hanna, C, Klein, E, Cox
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Cyclic nucleotides, cyclic nucleotide phosphodiesterase, and development in Myxococcus xanthus

Canadian Journal of Microbiology, 1978
Exogenous cyclic nucleotide phosphodiesterase (PD) accelerated fruiting body (FB) formation and increased territory size of aggregates in Myxococcus xanthus. Both guanosine 3′5′- monophosphate (cGMP) and guanosine 5′-monophosphate (GMP) were antagonistic to the PD effect.
H D, McCurdy, J, Ho, W J, Dobson
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Cyclic nucleotide phosphodiesterase from carrot

Phytochemistry, 1974
Abstract A cyclic nucleotide phosphodiesterase has been isolated and partially purified from carrot tap-root tissue. The properties of this enzyme are very different from cyclic AMP phosphodiesterases found in mammalian cells. A dialyzable inhibitor of carrot cyclic nucleotide phosphodiesterase was also isolated from carrot tissue.
R.M. Niles, M.S. Mount
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Cyclic Nucleotide Phosphodiesterases

2000
In multicellular organisms, cell functions are integrated through a large network of signals and homeostatic mechanisms that control the intracellular concentration of second messengers. This is a feature indispensable for the basal functions of the body, as well as for an efficient response to the continuous changes in the environment to which the ...
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[Phosphodiesterase of cyclic nucleotides].

Ukrainskii biokhimicheskii zhurnal (1978), 1981
Problems are considered on form multiplicity, purification and molecular weight of cyclic nucleotides phosphodiesterase. A supposition is made that the molecular weight of the catalytic subunit of the enzyme for most studied objects is about 60000. The catalytic subunit may form di- and trimers and be associated with regulatory proteins of different ...
R N, Etingof, I L, Dumler
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Platelet Cyclic Nucleotide Phosphodiesterases

1999
Currently, the two antiplatelet agents with proven efficacy are aspirin, which inhibits cyclooxygenase-dependent synthesis of thromboxane A2 (TXA2 ), and ticlopidine, which blocks the ability of ADP to inhibit stimulated adenyl cyclase. Both of these drugs have proven prophylactic uses in reducing the risk of thromboocclusive and thromboembolic ...
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CYCLIC NUCLEOTIDE PHOSPHODIESTERASES: PHARMACOLOGY, BIOCHEMISTRY AND FUNCTION

Pharmacology & Therapeutics, 1991
This article is a review of cyclic nucleotide phosphodiesterase(s) (CN PDE) from the point of view of the relationships between the newer aspects of the complex enzymology of CN PDE and recent major advances in CN PDE pharmacology. A consolidation of isozyme nomenclature to the proposed family designations is recommended.
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CYCLIC NUCLEOTIDE PHOSPHODIESTERASE AND CYCLIC AMP*

Annals of the New York Academy of Sciences, 1971
W J, Thompson, M M, Appleman
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Cyclic GMP-regulated cyclic nucleotide phosphodiesterases

Cellular Signalling, 1993
D J, Takemoto, K, Gonzalez, I, Udovichenko, J, Cunnick   +3 more
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