Extracellular modulation of the silkmoth sex pheromone receptor activity by cyclic nucleotides. [PDF]
PLoS ONE, 2014 Odorants and pheromones are essential to insects as chemical cues for finding food or an appropriate mating partner. These volatile compounds bind to olfactory receptors (Ors) expressed by olfactory sensory neurons.
Tatsuro Nakagawa, Kazushige Touhara
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Cyclic nucleotides in archaea: Cyclic di‐AMP in the archaeon Haloferax volcanii and its putative role [PDF]
MicrobiologyOpen, 2019 The role of cyclic nucleotides as second messengers for intracellular signal transduction has been well described in bacteria. One recently discovered bacterial second messenger is cyclic di‐adenylate monophosphate (c‐di‐AMP), which has been demonstrated
Frank Braun +6 more
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Modulation of Hyperpolarization-Activated Inward Current and Thalamic Activity Modes by Different Cyclic Nucleotides [PDF]
Frontiers in Cellular Neuroscience, 2018 The hyperpolarization-activated inward current, Ih, plays a key role in the generation of rhythmic activities in thalamocortical (TC) relay neurons.
Maia Datunashvili +11 more
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The effect of cCMP and cUMP on growth of Pseudomonas aeruginosa [PDF]
Frontiers in MicrobiologyThe aim of this study was to screen for possible biological effects of the non-canonical nucleotides 3’,5’-cyclic uridine monophosphate (cUMP) and 3’,5’-cyclic cytidine monophosphate (cCMP) on Pseudomonas aeruginosa beyond the already reported function ...
Christoph Risser +6 more
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Nucleotides as Bacterial Second Messengers
Molecules, 2023 In addition to comprising monomers of nucleic acids, nucleotides have signaling functions and act as second messengers in both prokaryotic and eukaryotic cells. The most common example is cyclic AMP (cAMP).
Mario E. Cancino-Diaz +3 more
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Crystallization as a selection force at the polymerization of nucleotides in a prebiotic context
iScience, 2023 Summary: Accumulation and selection of nucleotides is one of the most challenging problems surrounding the origin of the first RNA molecules on our planet.
Judit E. Šponer +6 more
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Life, 2021 Template-free nonenzymatic polymerization of 3′,5′ cyclic nucleotides is an emerging topic of the origin of life research. In the last ten years, a number of papers have been published addressing various aspects of this process.
Judit E. Šponer +6 more
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Functional Analysis of the Expanded Phosphodiesterase Gene Family in Toxoplasma gondii Tachyzoites
mSphere, 2022 Toxoplasma motility is both activated and suppressed by 3′,5′-cyclic nucleotide signaling. Cyclic GMP (cGMP) signaling through Toxoplasma gondii protein kinase G (TgPKG) activates motility, whereas cyclic AMP (cAMP) signaling through TgPKAc1 inhibits ...
William J. Moss +3 more
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Investigating cyclic nucleotide and cyclic dinucleotide binding to HCN channels by surface plasmon resonance. [PDF]
PLoS ONE, 2017 Hyperpolarization-activated cyclic nucleotide-modulated (HCN) channels control cardiac and neuronal rhythmicity. HCN channels contain cyclic nucleotide-binding domain (CNBD) in their C-terminal region linked to the pore-forming transmembrane segment with
Sebastien Hayoz +4 more
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