Novel mechanism of cyclic nucleotide crosstalk mediated by PKG-dependent proteasomal degradation of the Hsp90 client protein phosphodiesterase 3A [PDF]
Evgeny A. Zemskov +9 more
openalex +1 more source
Role of Dynamics in the Autoinhibition and Activation of the Hyperpolarization-activated Cyclic Nucleotide-modulated (HCN) Ion Channels [PDF]
Bryan VanSchouwen +4 more
openalex +1 more source
Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen +11 more
wiley +1 more source
Compartmentalized cyclic nucleotides have opposing effects on regulation of hypertrophic phospholipase Cε signaling in cardiac myocytes. [PDF]
Nash CA +4 more
europepmc +1 more source
Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha +13 more
wiley +1 more source
Comparative analysis of established and new biosensors for cyclic nucleotides [PDF]
Milde M +7 more
europepmc +1 more source
Nucleotide binding by the widespread high-affinity cyclic di-GMP receptor MshEN domain
Yu‐Chuan Wang +8 more
openalex +1 more source
Cyclic Nucleotide (cAMP and cGMP) Assays and Capture ELISA for Quantitative Analysis of Plasmodium falciparum Blood-stage Egress [PDF]
Fiona Hackett +3 more
openalex +1 more source

