Results 281 to 290 of about 121,582 (318)
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Phytochemistry, 2004
The natural occurrence of cyclic nucleotides in higher plants, formerly a topic of fierce debate, is now established, as is the presence of nucleotidyl cyclases and cyclic nucleotide phosphodiesterases capable of their synthesis and breakdown. Here we describe the significant properties of cyclic nucleotides, also outlining their second messenger ...
Russell P, Newton, Christopher J, Smith
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The natural occurrence of cyclic nucleotides in higher plants, formerly a topic of fierce debate, is now established, as is the presence of nucleotidyl cyclases and cyclic nucleotide phosphodiesterases capable of their synthesis and breakdown. Here we describe the significant properties of cyclic nucleotides, also outlining their second messenger ...
Russell P, Newton, Christopher J, Smith
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Arkhiv patologii, 1977
A survey of the available literature on the role of cyclic nucleotides (cyclic adenosine 3,5-monophosphate and cyclic guanosine 3,5-monophosphate) in the control over various aspects of cellular activity: regulation of growth and morphology of normal and tumorous cells, participation in differentiation of cells, blast-transformation, regulation of ...
Maynard H. Makman +2 more
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A survey of the available literature on the role of cyclic nucleotides (cyclic adenosine 3,5-monophosphate and cyclic guanosine 3,5-monophosphate) in the control over various aspects of cellular activity: regulation of growth and morphology of normal and tumorous cells, participation in differentiation of cells, blast-transformation, regulation of ...
Maynard H. Makman +2 more
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Cyclic nucleotide phosphodiesterases
Journal of Allergy and Clinical Immunology, 2001Cyclic nucleotide second messengers (cAMP and cGMP) play a central role in signal transduction and regulation of physiologic responses. Their intracellular levels are controlled by the complex superfamily of cyclic nucleotide phosphodiesterase (PDE) enzymes. Continuing advances in our understanding of the molecular pharmacology of these enzymes has led
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1990
Abstract Peptide hormones bind to specific receptors on the exterior of the cell, and activate particular signal transduction systems, thus eliciting a physiological response. One type of signal which has been shown to mediate the effects of many hormones on many cells types involves the production or degradation of cyclic nucleotides ...
Lakey, T, Pyne, Nigel, Murphy, G J
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Abstract Peptide hormones bind to specific receptors on the exterior of the cell, and activate particular signal transduction systems, thus eliciting a physiological response. One type of signal which has been shown to mediate the effects of many hormones on many cells types involves the production or degradation of cyclic nucleotides ...
Lakey, T, Pyne, Nigel, Murphy, G J
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Saturation of anti cyclic nucleotides antibodies by endogenous cyclic nucleotides
Biochemical and Biophysical Research Communications, 1979Abstract Rabbits immunized against cyclic AMP or cyclic GMP produce antibodies which are fully saturated by their respective endogenous cyclic nucleotides. This was proved a) in comparing radioimmunological measurements of cyclic nucleotides in antiserum and the binding site concentration determined by equilibrium dialysis, b) in showing the ...
D, Roux, M A, Delaage, H L, Cailla
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Cyclic Nucleotide Mapping of Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels
ACS Chemical Biology, 2014Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels play a central role in the regulation of cardiac and neuronal firing rate, and these channels can be dually activated by membrane hyperpolarization and by binding of cyclic nucleotides. cAMP has been shown to directly bind HCN channels and modulate their activity.
Moller, Stefan +8 more
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Cyclic Nucleotides and Neuroblastoma Differentiation
Nucleosides, Nucleotides and Nucleic Acids, 2004AbstractFor Abstract see ChemInform Abstract in Full Text.
MESSINA, ELISA +3 more
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Cyclic Nucleotides in Neuromuscular Transmission
Anesthesia & Analgesia, 1981A review of the research on cyclic nucleotides and neuromuscular transmission suggests that cAMP is involved in the release of transmitter from motor nerve endings. Lipid-soluble derivations of cAMP cause depolarization of unstimulated nerve endings and prolong the after potentials of stimulated nerve endings.
F G, Standaert, K L, Dretchen
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Cyclic Nucleotide-Gated Channels
2008Cyclic nucleotide-gated (CNG) channels are ion channels which are activated by the binding of cGMP or cAMP. The channels are important cellular switches which transduce changes in intracellular concentrations of cyclic nucleotides into changes of the membrane potential and the Ca2+ concentration.
Martin, Biel, Stylianos, Michalakis
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Experimental Cell Research, 1979
Abstract Polysphondylium violaceum is shown to produce and excrete cyclic nucleotides and to produce a cell-associated cyclic nucleotide phosphodiesterase(s). The amount of adenosine 3′,5′-cyclic monophosphate (cAMP) excreted by the amebae reaches a maximum during development when aggregation centers are just forming and then falls off rapidly ...
M H, Hanna, C, Klein, E, Cox
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Abstract Polysphondylium violaceum is shown to produce and excrete cyclic nucleotides and to produce a cell-associated cyclic nucleotide phosphodiesterase(s). The amount of adenosine 3′,5′-cyclic monophosphate (cAMP) excreted by the amebae reaches a maximum during development when aggregation centers are just forming and then falls off rapidly ...
M H, Hanna, C, Klein, E, Cox
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