Comparative molecular dynamics of two cyclic peptide inhibitors bound to the Zika virus NS2B/NS3 protease. [PDF]
Marinho CVS, de Oliveira MVD, Lima AH.
europepmc +1 more source
A self‐powered PCL/gelatin‐PVDF‐TrFE/MXene conjugated electrospun membrane integrates biocompatibility with enhanced piezoelectric responsiveness. Mechanical deformation is converted into localized electrical signals that stimulate wound‐repair cells proliferation and migration, promote angiogenesis and tissue remodeling, and accelerate full‐thickness ...
Diandian Li +11 more
wiley +1 more source
The Coalescence of a "Happy Accident" and an In Vitro Structure-Activity Panel: Increasing the Potency of a Cyclic Peptide Inhibitor to Thrombosis Initiation. [PDF]
Barreto GM +8 more
europepmc +1 more source
Advances in Bio‐Integrated Edge Computing Systems for Smart and Connected Health
This review explores advances in bio‐integrated edge computing for healthcare, focusing on co‐designing computing, sensing, and energy strategies to overcome integration and power challenges for optimized, decentralized operation. ABSTRACT Recent advances in bio‐integrated healthcare technologies have enabled continuous, high‐resolution monitoring and ...
Gyuwon Kim +4 more
wiley +1 more source
Targeting Melanoma-Specific Tyrosinase Disrupts Cytoskeleton Dynamics for Precision Apoptosis Induction by a De Novo Designed Cyclic Peptide. [PDF]
Zhao R +13 more
europepmc +1 more source
Biomass DNA: An Emerging Building Block for Advanced Materials
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley +1 more source
Machine learning-driven identification of DLL3 as a molecular target and development of a DLL3-binding cyclic peptide for glioblastoma. [PDF]
Xu D +15 more
europepmc +1 more source
Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction
The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu +2 more
wiley +1 more source
Construction and Functional Evaluation of Cyclic Peptide-Based CAR T Cells in Tumor Models. [PDF]
Meng X, Wu Q, Tsai YH.
europepmc +1 more source
Interface Dynamics in Biomolecular Condensates by High‐Speed AFM
High‐speed atomic force microscopy provides nanoscale structural dynamics at the liquid interface of biomolecular condensates, key elements in several cellular pathways. By addressing the challenges of low surface tension and condensate‐induced instabilities, we achieve nanometer spatial and sub‐second temporal resolution, revealing structural ...
Andreas Santamaria +6 more
wiley +1 more source

