Results 191 to 200 of about 2,011,052 (344)

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source

2D Assemblies Based on a Tetraphenylethylene D,L-Cyclic Peptide Scaffold. [PDF]

Angew Chem Int Ed Engl
Bayón-Fernández A, Torrón-Celada A, Méndez-Ardoy A, Coste M, Delgado-Gestoso D, Ulrich S, Montenegro J, Granja JR.   +7 more
europepmc   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Cyclic Peptide-Polymer Conjugate Characterization Using 193 nm Ultraviolet Photodissociation Tandem Mass Spectrometry. [PDF]

Anal Chem
Morgan TE, Theisen A, Ellacott S, Haris A, Wootton CA, Rho JY, Barrow MP, Bristow AWT, Perrier S, O'Connor PB.   +9 more
europepmc   +1 more source

A Trp-BODIPY cyclic peptide for fluorescence labelling of apoptotic bodies.

Chemical Communications, 2017
Ramon Subirós‐Funosas, Lorena Mendive-Tapia, J. Sot, J. Pound, N. Barth, Yaiza R. Varela, F. Goñi, M. Paterson, C. Gregory, F. Albericio, I. Dransfield, R. Lavilla, M. Vendrell   +12 more
semanticscholar   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Recent advances in controlling the internal and external properties of self-assembling cyclic peptide nanotubes and dimers.

Organic and biomolecular chemistry, 2017
Nuria Rodríguez-Vázquez, M. Amorín, J. Granja   +2 more
semanticscholar   +1 more source

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

A Nonviral Neo-Nucleocapsid for Cell-Specific RNA Delivery Developed by Pseudo-Cyclic Peptide Grafting and Directed Evolution. [PDF]

Angew Chem Int Ed Engl
Kanayama D, Terasaka N, Kato K, Okazaki S, Suga H.   +4 more
europepmc   +1 more source

pH-Responsive, Amphiphilic Core-Shell Supramolecular Polymer Brushes from Cyclic Peptide-Polymer Conjugates.

ACS Macro Letters, 2017
Sophie C. Larnaudie, Johannes C. Brendel, K. Jolliffe, S. Perrier   +3 more
semanticscholar   +1 more source