Anion recognition by cyclic peptides [PDF]
Chemical Communications, 2015 Cyclic peptides provide excellent scaffolds for anion recognition and improved binding affinity and selectivity has been achieved through peptide backbone rigidification and the introduction of side chains bearing anion recognition groups.
Elmes, Robert B. P. +1 more
openaire +5 more sources
Peptide oligomers from ultra-short peptides using sortase
Biochemistry and Biophysics Reports, 2017 Sortase A catalyzed ligation of ultra-short peptides leads to inter/intra-molecular transpeptidation to form either linear or cyclic oligomers dependent upon the peptide length.
Natalya Voloshchuk +3 more
doaj +1 more source
Novel Cyclic Peptides from Lethal Amanita Mushrooms through a Genome-Guided Approach
Journal of Fungi, 2021 Most species in the genus Amanita are ectomycorrhizal fungi comprising both edible and poisonous mushrooms. Some species produce potent cyclic peptide toxins, such as α-amanitin, which places them among the deadliest organisms known to mankind.
Shengwen Zhou +8 more
doaj +1 more source
Cyclic RGD-containing peptides: in silico exploration against BCL-X(L) [PDF]
The Ukrainian Biochemical Journal, 2023 Сyclic peptides attract attention for possible applications in cancer treatment. We examined the ability of six cyclic RGD-containing peptides-based compounds to inhibit B-cell lymphoma-extra-large (Bcl-XL) (PDB ID: 3zk6) using the in silico method.
A. K. Oyebamiji +5 more
doaj +1 more source
Immobilization by surface conjugation of cyclic peptides for effective mimicry of the HCV-envelope E2 protein as a strategy toward synthetic vaccines [PDF]
, 2018 Mimicry of the binding interface of antibody-antigen interactions using peptide-based modulators (i.e. epitope mimics) has promising applications for vaccine design.
Dunlop, James I. +5 more
core +2 more sources
Anti-oxidative stress mechanism of cyclic dipeptide in distiller's grains of strong-flavor Baijiu [PDF]
Zhongguo niangzaoIn this study, the in vitro antioxidant activity of free peptides in distiller's grains of strong-flavor (Nongxiangxing) Baijiu was determined by measuring the free radical scavenging rate of 1,1-diphenyl-2-trinitrophenylhydrazine (DPPH).
GUO Yan, LIAO Qinjian, ZHENG Jia, WANG Fang, YANG Hao, ZHOU Hanling, SU Jian
doaj +1 more source
Cyclo19,31[D-Cys19]-uPA19-31 is a potent competitive antagonist of the interaction of urokinase-type plasminogen activator with its receptor (CD87) [PDF]
, 2001 Urokinase-type plasminogen activator (uPA) represents a central molecule in pericellular proteolysis and is implicated in a variety of physiological and pathophysiological processes such as tissue remodelling, wound healing, tumor invasion, and ...
Arroyo de Prada, Nuria +10 more
core +1 more source
G3: Genes, Genomes, Genetics, 2022 In recent years, a variety of fungal cyclic peptides with interesting bioactivities have been discovered. For many of these peptides, the biosynthetic pathways are unknown and their elucidation often holds surprises.
Eva Vogt +3 more
doaj +1 more source
Open Chemistry, 2021 Acacia honey is characterized by high nutritional, antioxidant, antibacterial and immuno-modulatory values. This work investigated the presence of short and cyclic peptides in Acacia and Ziziphus honey samples.
ALaerjani Wed Mohammed Ali +7 more
doaj +1 more source
Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex. [PDF]
, 2015 Cyclic peptide natural products have evolved to exploit diverse protein targets, many of which control essential cellular processes. Inspired by a series of cyclic peptides with partially elucidated structures, we designed synthetic variants of ternatin,
Carelli, Jordan D +8 more
core +2 more sources