Results 31 to 40 of about 864,219 (292)

Novel Cyclic Peptides from Lethal Amanita Mushrooms through a Genome-Guided Approach

open access: yesJournal of Fungi, 2021
Most species in the genus Amanita are ectomycorrhizal fungi comprising both edible and poisonous mushrooms. Some species produce potent cyclic peptide toxins, such as α-amanitin, which places them among the deadliest organisms known to mankind.
Shengwen Zhou   +8 more
doaj   +1 more source

Antimicrobial Peptides and Skin: A Paradigm of Translational Medicine [PDF]

open access: yes, 2012
Antimicrobial peptides (AMPs) are small, cationic, amphiphilic peptides with broad-spectrum microbicidal activity against both bacteria and fungi. In mammals, AMPs form the first line of host defense against infections and generally play an important ...
Schöllmann, C.   +3 more
core   +1 more source

Cyclic RGD-containing peptides: in silico exploration against BCL-X(L) [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2023
Сyclic peptides attract attention for possible applications in cancer treatment. We examined the abili­ty of six cyclic RGD-containing peptides-based compounds to inhibit B-cell lymphoma-extra-large (Bcl-XL) (PDB ID: 3zk6) using the in silico method.
A. K. Oyebamiji   +5 more
doaj   +1 more source

Presence of short and cyclic peptides in Acacia and Ziziphus honeys may potentiate their medicinal values

open access: yesOpen Chemistry, 2021
Acacia honey is characterized by high nutritional, antioxidant, antibacterial and immuno-modulatory values. This work investigated the presence of short and cyclic peptides in Acacia and Ziziphus honey samples.
ALaerjani Wed Mohammed Ali   +7 more
doaj   +1 more source

Genome sequences of Rhizopogon roseolus, Mariannaea elegans, Myrothecium verrucaria, and Sphaerostilbella broomeana and the identification of biosynthetic gene clusters for fungal peptide natural products

open access: yesG3: Genes, Genomes, Genetics, 2022
In recent years, a variety of fungal cyclic peptides with interesting bioactivities have been discovered. For many of these peptides, the biosynthetic pathways are unknown and their elucidation often holds surprises.
Eva Vogt   +3 more
doaj   +1 more source

Peptídeos cíclicos de biomassa vegetal: características, diversidade, biossíntese e atividades biológicas Cyclic peptide from plant biomass: chemical features and diversity, biosynthesis and biological activities

open access: yesQuímica Nova, 2009
Natural peptides are outstanding as the most promising macromolecules in the search for new drugs, especially those of cyclic nature. The higher plants revealed a very peculiar composition of their cyclic peptides, which distinguish themselves by a "head-
Douglas Gatte Picchi   +4 more
doaj   +1 more source

Cyclic peptides- small and big and their conformational aspects [PDF]

open access: yes, 1985
Cyclic peptides form an interesting class of compounds for study by conformational analysis, by virtue of their unique conformational features and biological properties.
Ramakrishnan, C.   +2 more
core   +1 more source

Directed Evolution of Bicyclic Peptides for Therapeutic Application

open access: yesCHIMIA, 2013
Many naturally occurring cyclic peptides or derivatives thereof are used as therapeutics such as the human hormones vasopressin and oxytocin or the antibiotics vancomycin and daptomycin.
Philippe Diderich, Christian Heinis
doaj   +1 more source

Isolating cyclic peptides from linear peptides

open access: yes, 2023
Poster and abstract presented at the FYRE in STEM Showcase, 2023.Research project completed at the Department of Chemistry and Biochemistry.For decades, medicines treating ailments from autoimmune diseases to fungal infections have included peptides ...
Mandapaka, Hyma   +2 more
core   +1 more source

Natural Cyclic Peptides as an Attractive Modality for Therapeutics: A Mini Review

open access: yesMolecules, 2018
Peptides are important biomolecules which facilitate the understanding of complex biological processes, which in turn could be serendipitous biological targets for future drugs. They are classified as a unique therapeutic niche and will play an important
Muna Ali Abdalla, Lyndy J. McGaw
doaj   +1 more source

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