Results 31 to 40 of about 109,209 (296)

Enhancing Cell Penetration Efficiency of Cyclic Oligoarginines Using Rigid Scaffolds

open access: yesPharmaceutics, 2023
Delivering therapeutic agents into cells has always been a major challenge. In recent years, cyclization emerged as a tool for designing CPPs to increase their internalization and stability.
Csaba Bató   +2 more
doaj   +1 more source

Antimicrobial Peptides and Skin: A Paradigm of Translational Medicine [PDF]

open access: yes, 2012
Antimicrobial peptides (AMPs) are small, cationic, amphiphilic peptides with broad-spectrum microbicidal activity against both bacteria and fungi. In mammals, AMPs form the first line of host defense against infections and generally play an important ...
Schöllmann, C.   +3 more
core   +1 more source

Peptide oligomers from ultra-short peptides using sortase

open access: yesBiochemistry and Biophysics Reports, 2017
Sortase A catalyzed ligation of ultra-short peptides leads to inter/intra-molecular transpeptidation to form either linear or cyclic oligomers dependent upon the peptide length.
Natalya Voloshchuk   +3 more
doaj   +1 more source

Anti-oxidative stress mechanism of cyclic dipeptide in distiller's grains of strong-flavor Baijiu [PDF]

open access: yesZhongguo niangzao
In this study, the in vitro antioxidant activity of free peptides in distiller's grains of strong-flavor (Nongxiangxing) Baijiu was determined by measuring the free radical scavenging rate of 1,1-diphenyl-2-trinitrophenylhydrazine (DPPH).
GUO Yan, LIAO Qinjian, ZHENG Jia, WANG Fang, YANG Hao, ZHOU Hanling, SU Jian
doaj   +1 more source

Cyclic RGD-containing peptides: in silico exploration against BCL-X(L) [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2023
Сyclic peptides attract attention for possible applications in cancer treatment. We examined the abili­ty of six cyclic RGD-containing peptides-based compounds to inhibit B-cell lymphoma-extra-large (Bcl-XL) (PDB ID: 3zk6) using the in silico method.
A. K. Oyebamiji   +5 more
doaj   +1 more source

Methionine epimerization in cyclic peptides

open access: yesRSC Advances, 2021
One step regioselective methionine epimerization in cyclic peptides followed by selective functionalization leads to chemical novelty.
Pramodkumar D. Jadhav   +5 more
openaire   +3 more sources

Novel Cyclic Peptides from Lethal Amanita Mushrooms through a Genome-Guided Approach

open access: yesJournal of Fungi, 2021
Most species in the genus Amanita are ectomycorrhizal fungi comprising both edible and poisonous mushrooms. Some species produce potent cyclic peptide toxins, such as α-amanitin, which places them among the deadliest organisms known to mankind.
Shengwen Zhou   +8 more
doaj   +1 more source

Presence of short and cyclic peptides in Acacia and Ziziphus honeys may potentiate their medicinal values

open access: yesOpen Chemistry, 2021
Acacia honey is characterized by high nutritional, antioxidant, antibacterial and immuno-modulatory values. This work investigated the presence of short and cyclic peptides in Acacia and Ziziphus honey samples.
ALaerjani Wed Mohammed Ali   +7 more
doaj   +1 more source

Genome sequences of Rhizopogon roseolus, Mariannaea elegans, Myrothecium verrucaria, and Sphaerostilbella broomeana and the identification of biosynthetic gene clusters for fungal peptide natural products

open access: yesG3: Genes, Genomes, Genetics, 2022
In recent years, a variety of fungal cyclic peptides with interesting bioactivities have been discovered. For many of these peptides, the biosynthetic pathways are unknown and their elucidation often holds surprises.
Eva Vogt   +3 more
doaj   +1 more source

Synthesis of the chlorofusin cyclic peptide [PDF]

open access: yesTetrahedron, 2009
An efficient and convergent solution-phase synthesis of the cyclic peptide of the natural product chlorofusin, a reported inhibitor of the MDM2-p53 interaction, is detailed.
Sang Yeul, Lee, Dale L, Boger
openaire   +2 more sources

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