Peptide oligomers from ultra-short peptides using sortase
Biochemistry and Biophysics Reports, 2017 Sortase A catalyzed ligation of ultra-short peptides leads to inter/intra-molecular transpeptidation to form either linear or cyclic oligomers dependent upon the peptide length.
Natalya Voloshchuk +3 more
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Cyclic RGD-containing peptides: in silico exploration against BCL-X(L) [PDF]
The Ukrainian Biochemical Journal, 2023 Сyclic peptides attract attention for possible applications in cancer treatment. We examined the ability of six cyclic RGD-containing peptides-based compounds to inhibit B-cell lymphoma-extra-large (Bcl-XL) (PDB ID: 3zk6) using the in silico method.
A. K. Oyebamiji +5 more
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A comprehensive evaluation of the activity and selectivity profile of ligands for RGD-binding integrins [PDF]
, 2017 Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation.
Cavalcanti-Adam, Elisabetta Ada +12 more
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Anti-oxidative stress mechanism of cyclic dipeptide in distiller's grains of strong-flavor Baijiu [PDF]
Zhongguo niangzaoIn this study, the in vitro antioxidant activity of free peptides in distiller's grains of strong-flavor (Nongxiangxing) Baijiu was determined by measuring the free radical scavenging rate of 1,1-diphenyl-2-trinitrophenylhydrazine (DPPH).
GUO Yan, LIAO Qinjian, ZHENG Jia, WANG Fang, YANG Hao, ZHOU Hanling, SU Jian
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Novel Cyclic Peptides from Lethal Amanita Mushrooms through a Genome-Guided Approach
Journal of Fungi, 2021 Most species in the genus Amanita are ectomycorrhizal fungi comprising both edible and poisonous mushrooms. Some species produce potent cyclic peptide toxins, such as α-amanitin, which places them among the deadliest organisms known to mankind.
Shengwen Zhou +8 more
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Analytical Rebridging Monte Carlo: Application to cis/trans Isomerization in Proline-Containing, Cyclic Peptides [PDF]
, 1999 We present a new method, the analytical rebridging scheme, for Monte Carlo simulation of proline-containing, cyclic peptides. The cis/trans isomerization is accommodated by allowing for two states of the amide bond.
Higgins K. A. +4 more
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Cyclo19,31[D-Cys19]-uPA19-31 is a potent competitive antagonist of the interaction of urokinase-type plasminogen activator with its receptor (CD87) [PDF]
, 2001 Urokinase-type plasminogen activator (uPA) represents a central molecule in pericellular proteolysis and is implicated in a variety of physiological and pathophysiological processes such as tissue remodelling, wound healing, tumor invasion, and ...
Arroyo de Prada, Nuria +10 more
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G3: Genes, Genomes, Genetics, 2022 In recent years, a variety of fungal cyclic peptides with interesting bioactivities have been discovered. For many of these peptides, the biosynthetic pathways are unknown and their elucidation often holds surprises.
Eva Vogt +3 more
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Trypsin inhibition by macrocyclic and open-chain variants of the squash inhibitor MCoTI-II [PDF]
, 2005 MCoTl-I and MCoTl-II from the seeds of Momordica cochinchinensis are inhibitors of trypsin-like proteases and the only known members of the large family of squash inhibitors that are cyclic and contain an additional loop connecting the amino- and the ...
Avrutina, Olga +6 more
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Open Chemistry, 2021 Acacia honey is characterized by high nutritional, antioxidant, antibacterial and immuno-modulatory values. This work investigated the presence of short and cyclic peptides in Acacia and Ziziphus honey samples.
ALaerjani Wed Mohammed Ali +7 more
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