Results 41 to 50 of about 1,916,855 (274)

Anti-oxidative stress mechanism of cyclic dipeptide in distiller's grains of strong-flavor Baijiu [PDF]

Zhongguo niangzao
In this study, the in vitro antioxidant activity of free peptides in distiller's grains of strong-flavor (Nongxiangxing) Baijiu was determined by measuring the free radical scavenging rate of 1,1-diphenyl-2-trinitrophenylhydrazine (DPPH).
GUO Yan, LIAO Qinjian, ZHENG Jia, WANG Fang, YANG Hao, ZHOU Hanling, SU Jian
doaj   +1 more source

Genome sequences of Rhizopogon roseolus, Mariannaea elegans, Myrothecium verrucaria, and Sphaerostilbella broomeana and the identification of biosynthetic gene clusters for fungal peptide natural products

G3: Genes, Genomes, Genetics, 2022
In recent years, a variety of fungal cyclic peptides with interesting bioactivities have been discovered. For many of these peptides, the biosynthetic pathways are unknown and their elucidation often holds surprises.
Eva Vogt, Christopher M Field, Lukas Sonderegger, Markus Künzler   +3 more
doaj   +1 more source

Small Natural Cyclic Peptides from DBAASP Database. [PDF]

Pharmaceuticals (Basel)
Antimicrobial peptides (AMPs) are promising tools for combating microbial resistance. However, their therapeutic potential is hindered by two intrinsic drawbacks—low target affinity and poor in vivo stability.
Alimbarashvili E, Samsonidze N, Grigolava M, Pirtskhalava M.   +3 more
europepmc   +2 more sources

Presence of short and cyclic peptides in Acacia and Ziziphus honeys may potentiate their medicinal values

Open Chemistry, 2021
Acacia honey is characterized by high nutritional, antioxidant, antibacterial and immuno-modulatory values. This work investigated the presence of short and cyclic peptides in Acacia and Ziziphus honey samples.
ALaerjani Wed Mohammed Ali, Abu-Melha Saraa Abdullah, Khan Khalid Ali, Ghramh Hamed A., Alalmie Ali Yahya A., Alshareef Rahaf Mohammed Hussein, AL-Shehri Badria M., Mohammed Mohammed Elimam Ahamed   +7 more
doaj   +1 more source

HighFold-MeD: a Rosetta distillation model to accelerate structure prediction of cyclic peptides with backbone N-methylation and D-amino acids. [PDF]

J Cheminform
Abstract Cyclic peptides with backbone N-methylated amino acids (BNMeAAs) and D-amino acids (D-AAs) have gained increasing attention for their stability, membrane permeability, and other therapeutic potentials.
Cao Z, Cao S, Wang L, Wang Z, Mao Q, Guo J, Duan H.   +6 more
europepmc   +2 more sources

Natural Cyclic Peptides: Synthetic Strategies and Biomedical Applications. [PDF]

Biomedicines
Natural cyclic peptides, a diverse class of bioactive compounds, have been isolated from various natural sources and are renowned for their extensive structural variability and broad spectrum of medicinal properties.
Buchanan D, Mori S, Chadli A, Panda SS.
europepmc   +2 more sources

Peptídeos cíclicos de biomassa vegetal: características, diversidade, biossíntese e atividades biológicas Cyclic peptide from plant biomass: chemical features and diversity, biosynthesis and biological activities

Química Nova, 2009
Natural peptides are outstanding as the most promising macromolecules in the search for new drugs, especially those of cyclic nature. The higher plants revealed a very peculiar composition of their cyclic peptides, which distinguish themselves by a "head-
Douglas Gatte Picchi, Wanessa Fernanda Altei, Mônica Sue Saito, Vanderlan da Silva Bolzani, Eduardo Maffud Cilli   +4 more
doaj   +1 more source

Sweetening Cyclic Peptide Libraries [PDF]

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +2 more sources

Cyclic peptides: A powerful instrument for advancing biomedical nanotechnologies and drug development.

Journal of Pharmaceutical and Biomedical Analysis
Cyclic peptides have emerged as an essential tool in the advancement of biomedical nanotechnologies, offering unique structural and functional advantages over linear peptides.
Paul Cristian Martian, M. Tertiș, Denisa Leonte, N. Hădade, Cecilia Cristea, O. Crișan   +5 more
semanticscholar   +1 more source

Understanding Cell Penetration of Cyclic Peptides.

Chemical Reviews, 2019
Approximately 75% of all disease-relevant human proteins, including those involved in intracellular protein-protein interactions (PPIs), are undruggable with the current drug modalities (i.e., small molecules and biologics).
Patrick G. Dougherty, Ashweta Sahni, D. Pei   +2 more
semanticscholar   +1 more source