Molecular model for the self-assembly of the cyclic lipodepsipeptide pseudodesmin A [PDF]
, 2019 Self-assembly of peptides into supramolecular structures represents an active field of research with potential applications ranging from material science to medicine.
Crowet, Jean-Marc +6 more
core +4 more sources
Natural Cyclic Peptides as an Attractive Modality for Therapeutics: A Mini Review
Molecules, 2018 Peptides are important biomolecules which facilitate the understanding of complex biological processes, which in turn could be serendipitous biological targets for future drugs. They are classified as a unique therapeutic niche and will play an important
Muna Ali Abdalla, Lyndy J. McGaw
doaj +1 more source
Royal Society Open Science, 2021 Improving the sustainability of synthesis is a major goal in green chemistry, which has been greatly aided by the development of asymmetric transition metal catalysis.
Richard C. Brewster +3 more
doaj +1 more source
Methionine epimerization in cyclic peptides
RSC Advances, 2021 One step regioselective methionine epimerization in cyclic peptides followed by selective functionalization leads to chemical novelty.
Pramodkumar D. Jadhav +5 more
openaire +3 more sources
Channel-forming activity of syringopeptin 25 A in mercury-supported phospholipid monolayers and negatively charged bilayers [PDF]
, 2016 Interactions of the cationic lipodepsipeptide syringopeptin 25 A (SP25A) with mercury-supported dioleoylphosphatidylcholine (DOPC), dioleoylphosphatidylserine (DOPS) and dioeleoylphosphatidic acid (DOPA) self-assembled monolayers (SAMs) were investigated
Becucci, Lucia +4 more
core +2 more sources
Microfluidics-based liquid chromatography/mass spectrometry multiple reaction monitoring approach for the relative quantification of Burkholderia cenocepacia secreted virulence factors [PDF]
, 2018 Rationale: Burkholderia cenocepacia is an opportunistic pathogen that is commonly isolated from patients with cystic fibrosis (CF). Quorum sensing has been suggested to play a role in the activity of type II and type VI secretion systems and the release ...
Daled, Simon +6 more
core +2 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds. [PDF]
, 2011 Backbone N-methylation is common among peptide natural products and has a substantial impact on both the physical properties and the conformational states of cyclic peptides.
Bauman, Jonathan N +16 more
core +1 more source
Neural Stem Cell Spreading on Lipid Based Artificial Cell Surfaces, Characterized by Combined X-ray and Neutron Reflectometry [PDF]
, 2010 We developed a bioadhesive coating based on a synthetic peptide-conjugate (AK-cycloRGDfC]) which contains multiples of the arginyl-glycyl-aspartic acid (RGD) amino acid sequence.
Bert Nickel +9 more
core +3 more sources
Janus cyclic peptide–polymer nanotubes [PDF]
Nature Communications, 2013 Self-assembled nanotubular structures have numerous potential applications but these are limited by a lack of control over size and functionality. Controlling these features at the molecular level may allow realization of the potential of such structures.
Maarten, Danial +4 more
openaire +2 more sources