Results 71 to 80 of about 8,950,425 (295)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Quasi-cyclic Generalized LDPC codes with low error floors [PDF]

, 2008
In this paper, a novel methodology for designing structured generalized LDPC (G-LDPC) codes is presented. The proposed design results in quasi-cyclic G-LDPC codes for which efficient encoding is feasible through shift-register-based circuits.
Ryan, William E., G. Liva, M. Chiani, Liva, Gianluigi, W.E. Ryan, Chiani, Marco, W. E. Ryan   +6 more
core   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Monotonic, cyclic and post-cyclic performances of single-helix anchor in residual soil of sandstone

Journal of Rock Mechanics and Geotechnical Engineering, 2019
Helical anchors are commonly used in Brazil for guyed transmission towers subjected to static and cyclic wind loads. In most cases, these anchors are installed in tropical residual soil, a micro-structured material in which the shear strength is provided by soil bonding.
José Antonio Schiavon, Cristina de Hollanda Cavalcanti Tsuha, Luc Thorel   +2 more
openaire   +3 more sources

Analysis of cyclic delay diversity on DVB-H systems over spatially correlated channel [PDF]

, 2007
The objective of this work is to research and analyze the performance of Cyclic Delay Diversity (CDD) with two transmit antenna on DVB-H systems operating in spatially correlated channel. It is shown in this paper that CDD can achieve desirable transmit
Bari, RD, Loo, KK, Cosmas, J, Zhang, Y, Bard, M, Loo, J., Cosmas, J., Di Bari, R., Bard, M., Zhang, Y.   +9 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Preparation and characterization of in situ polymerized cyclic butylene terephthalate/graphene nanocomposites [PDF]

, 2012
Graphene reinforced cyclic butylene terephthalate (CBT) matrix nanocomposites were prepared and characterized by mechanical and thermal methods. These nanocomposites containing different amounts of graphene (up to 5 wt%) were prepared by melt mixing with
Hajba, Sándor, Karger-Kocsis, József, Czigány, Tibor, Balogh, Gábor   +3 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Development of Analytical Model for Bonding of CFRP Rod in Concrete Subjected to Cyclic Loads

Applied Sciences
Recent material science advances have resulted in the use of High-Performance Concrete (HPC) and Ultra-High-Performance Concrete (UHPC) in superstructures, which were chosen for their superior strength.
Arash Azarkerdar, Farzad Hejazi
doaj   +1 more source