Results 91 to 100 of about 126,861 (303)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

Elasto-plasticity and pore-pressure coupled analysis on the pullout behaviors of a plate anchor

open access: yesTheoretical and Applied Mechanics Letters, 2015
A numerical method is proposed for the elasto-plasticity and pore-pressure coupled analysis on the pullout behaviors of a plate anchor. The bounding-surface plasticity (BSP) model combined with Biot’s consolidation theory is employed to simulate the ...
Cun Hu, Fu-Ping Gao
doaj   +1 more source

A fully implicit multi-axial solution strategy for direct ratchet boundary evaluation : implementation and comparison [PDF]

open access: yes, 2012
Ensuring sufficient safety against ratcheting is a fundamental requirement in pressure vessel design. However, determining the ratchet boundary using a full elastic plastic finite element analysis can be problematic and a number of direct methods have ...
Chen, Haofeng   +2 more
core  

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

Surface Morphology and Its Influence on Cyclic Deformation Behavior of High-Mn TWIP Steel

open access: yesMetals, 2018
In this study, the dependence of the cyclic deformation behavior on the surface morphology of metastable austenitic HSD® 600 TWinning Induced Plasticity (TWIP) steel was investigated.
Matthias W. Klein   +2 more
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Shakedown behaviour of composite cylinders with cross holes [PDF]

open access: yes, 2010
In this study, both the lower and upper bound shakedown limits of a closed-end composite cylinder with or without a cross hole subject to constant internal pressure and a cyclic thermal gradient are calculated by the Linear Matching Method (LMM ...
Chen, Haofeng   +3 more
core  

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu   +10 more
wiley   +1 more source

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