Results 81 to 90 of about 126,861 (303)

Modelling Cyclic Behaviour of Martensitic Steel with J2 Plasticity and Crystal Plasticity

open access: yesMaterials, 2019
In order to capture the stress-strain response of metallic materials under cyclic loading, it is necessary to consider the cyclic hardening behaviour in the constitutive model. Among different cyclic hardening approaches available in the literature, the Chaboche model proves to be very efficient and convenient to model the kinematic hardening and ...
Hafiz Muhammad Sajjad   +5 more
openaire   +4 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Comparison of two models of numerical simulation of low cycle fatigue of a plastic material with small grid inclusions [PDF]

open access: yes, 2013
Theory of Cells and a numerical FE method based on strain cyclic plasticity, damage model and technology of died elements were used for a prediction of the fatigue life of a metal matrix composite material.
Azmetov, Khakim   +2 more
core  

Dynamic response of a damaging masonry wall [PDF]

open access: yes, 2017
A nonlocal damage-plastic model is adopted to describe the nonlinear structural response of masonry structures. The model, based on a macromechanical approach, accounts for strength and stiffness degradation with hysteretic dissipation typically ...
Cristina Gatta   +2 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Cyclic Elasto-Plastic Behaviour of 51CrV4 Steel for Railway Parabolic Leaf Spring Design

open access: yesApplied Sciences
Parabolic leaf springs are components typically found in suspensions of freight railway rolling stock. These components are produced in high-strength alloyed steel, DIN 51CrV4, to resist severe loading and environmental conditions. Despite the material’s
Vítor M. G. Gomes   +3 more
doaj   +1 more source

Creep-fatigue life assessment of cruciform weldments using the linear matching method [PDF]

open access: yes, 2013
This paper presents a creep-fatigue life assessment of a cruciform weldment made of the steel AISI type 316N(L) and subjected to reversed bending and cyclic dwells at 550C using the Linear Matching Method (LMM) and considering different weld zones.
Chen, Haofeng, Gorash, Yevgen
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Endothelial Plasticity: Shifting Phenotypes through Force Feedback

open access: yesStem Cells International, 2016
The endothelial lining of the vasculature is exposed to a large variety of biochemical and hemodynamic stimuli with different gradients throughout the vascular network.
Guido Krenning   +4 more
doaj   +1 more source

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