Results 71 to 80 of about 126,861 (303)
Stiffness of clays and silts: Modeling considerations [PDF]
, 2014 A large database has recently been published that details the development of new empirical expressions for the stiffness reduction with strain of clays and silts.
Bolton, Malcolm, Vardanega, Paul J
core +2 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Integrating the Chaboche Hardening Model into Phase Field Frameworks: A Numerical Study of Fatigue Crack Growth in S275 Mild Steel [PDF]
MATEC Web of ConferencesIn this research work, we present an implementation of the Chaboche hardening law within a phase field model to predict fatigue crack growth under cyclic plasticity in metals.
Zayani Iheb, Hamdi Adel, Mansouri Khalil
doaj +1 more source
Galectin-12 in Cellular Differentiation, Apoptosis and Polarization. [PDF]
, 2018 Galectin-12 is a member of a family of mammalian lectins characterized by their affinity for β-galactosides and consensus amino acid sequences. The protein structure consists of a single polypeptide chain containing two carbohydrate-recognition domains ...
Liu, Fu-Tong, Wan, Lei, Yang, Ri-Yao
core +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Thermo-mechanical FE model with memory effect for 304L austenitic stainless steel presenting microstructure gradient [PDF]
, 2012 The main purpose of this study is to determine, via a three dimensions Finite Element analysis (FE), the stress and strain fields at the inner surface of a tubular specimen submitted to thermo-mechanical fatigue.
Bompard, Philippe +5 more
core +6 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
A new accelerated technique for validation of cyclic plasticity models
MATEC Web of Conferences, 2018 This contribution presents a new methodology of fatigue tests evaluation based on digital image correlation application. The full-field strain analysis brings the possibility of 3D strain measurement evaluation on a curved part of specimen standardly ...
Halama Radim +3 more
doaj +1 more source
Numerical simulation of ratcheting and fatigue behaviour of mitred pipe bends under in-plane bending and internal pressure [PDF]
, 2013 This paper investigates the ratcheting and fatigue behaviour of 90 degree single unreinforced mitred pipe bends subjected to a cyclic in-plane closing moment with a non-zero mean value and constant internal pressure. An experiment was conducted to induce
Hamilton, Robert +3 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source