Results 71 to 80 of about 46,614 (307)
, 2013 This paper investigates the ratcheting and fatigue behaviour of 90 degree single unreinforced mitred pipe bends subjected to a cyclic in-plane closing moment with a non-zero mean value and constant internal pressure. An experiment was conducted to induce
Wood, James +3 more
core +1 more source
Thermal effect of plastic dissipation at the crack tip on the stress intensity factor under cyclic loading [PDF]
, 2011 The authors acknowledge Arts et Métiers ParisTech and Fondation Arts et Métiers for the financial support of Paul C. Paris’ stay at LAMEFIP in 2009. The encouragement of Prof. Ivan Iordanoff, Director of LAMEFIP, is acknowledged with thanks.
PARIS, Paul C. +8 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Constitutive modelling of the behaviour of clays under cyclic loading
, 1989 Includes bibliography.This research work involved the implementation of a constitutive model based on plasticity theory to model the behaviour of a clay under cyclic loading.
Sellers, E J
core
Ratchet analysis of structures under a generalised cyclic load history
, 2014 This paper introduces a new approach based upon the Linear Matching Method in order to obtain the ratchet limit of structures subjected to an arbitrary thermo-mechanical load history. This method varies from the traditional Linear Matching Method ratchet
Lytwyn, Michael +5 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Cyclic J integral using linear matching method
, 2012 The extended version of the latest Linear Matching Method (LMM) has the capability to evaluate the stable cyclic response, which produces cyclic stresses, residual stresses and plastic strain ranges for the low cycle fatigue assessment with cyclic load ...
Chen, Haofeng, Chen, Weihang
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
A new bounding-surface plasticity model for cyclic behaviors of saturated clay
, 2015 A new combined isotropic-kinematic hardening rule is proposed based on the concept of the generalized homological center and the generalization of Masing's rule.
Liu, HX (reprint author), Tianjin Univ, Sch Civil Engn, Tianjin 300072, Peoples R China. +2 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source