Results 151 to 160 of about 332,414 (335)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Behaviour of steel fibre reinforced concrete under cyclic compressive loading [PDF]

open access: yes, 2006
An experimental study was carried out to investigate the behaviour of steel fibre reinforced concrete under cyclic compressive loading. Cylindrical specimens containing two volume fractions (one percent and two percent) of steel fibres and plain concrete
Choubey, U. B., Shukla, Mukesh
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Crystal plasticity simulation of the effect of grain size on the fatigue behavior of polycrystalline Inconel 718

open access: yes, 2018
A microstructure-based model that accounts for the effect of grain size has been developed to study the effect of grain size on the fatigue life of Inconel 718 alloys.
Cruzado, A.   +3 more
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Evaluation of Excess Pore Water Pressure Build-up During Cyclic Triaxial Tests on a Non-plastic Silt

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi, 2018
Cyclicloading is responsible for pore water pressure buildup, which may later cause liquefactionand surface settlements. Recent studies emphasize that as the pore waterpressure equalizes to initial confining stress, cyclic stress ratio andrelative ...
Eyyüb Karakan   +2 more
doaj  

Strain Limits for Concrete Filled Steel Tubes in AASHTO Seismic Provisions [PDF]

open access: yes, 2013
INE/AUTC 13 ...
King Brown, Nicole   +2 more
core  

Home - About - Disclaimer - Privacy