Results 91 to 100 of about 904,141 (304)
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
, 2016 CpRuCl(cod)/NH4PF6 (Cp = cyclopentadienyl, cod = 1,5-cyclooctadiene) is an effective catalyst system for the allylic substitution of cyclic allyl carbonates with nucleophiles.
Teruyuki Kondo (1685632) +2 more
core +2 more sources
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Multi-Sample Thermobalance for Rapid Cyclic Oxidation Under Controlled Atmosphere [PDF]
, 2004 When testing the resistance to oxidation of high temperature materials, the cyclic oxidation test is used as a reference because it integrates isothermal oxidation kinetics, oxide scale adherence, mechanical stresses, metallic alloy and oxide mechanical ...
Salabura, Jean-Claude, Monceau, Daniel
core +1 more source
International Journal of Electrochemical Science, 2015 In this study, digital simulations were performed for cyclic voltammograms (CV) obtained at different scan rates (0.2 to 1.0 V/s) for the oxidatively-promoted CO-substitution reaction by PPh3 in the bimetallic FvCo2(CO)4,1, in CH2Cl2/0.05 M [NBu4][B(C6F5)
Sameerah I. Al-Saeedi +2 more
doaj +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Currency substitution and money demand in Euroland [PDF]
This papers tests the stability of the demand for money in the euro area in the context of an open economy. A sample consisting of quarterly data covering the 1982:2-1999:3 period is considered.
Miguel Lebre de Freitas
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Derivation of the Hicks Elasticity of Substitution from the Input Distance Function [PDF]
The Hicks or direct elasticity of substitution is traditionally derived from the production function. This paper exploits duality theory to present a more general derivation from the input distance function, which is exactly dual to the Shadow Elasticity
Stern, David I.
core