Results 71 to 80 of about 71,348 (303)

Ni-induced electronic modulation and structural resilience in TiMn-based AB2-type alloys for ultra-stable hydrogen storage

Nano Research Energy
TiMn-based AB2-type alloys have emerged as promising candidates for large-scale hydrogen storage applications due to their high theoretical capacity, room-temperature reversibility, and cost-effectiveness.
Wenfeng Qiao, Prof. Wanqiang Liu, Dongming Yin, Nan Ding, Yufei Liu, Haotian Sun, Ying Wang, Zhaomin Wang, Chunli Wang, Limin Wang, Jianguang Yuan, Yong Cheng   +11 more
doaj   +1 more source

Nucleophilic Substitution at Tetracoordinate Phosphorus. Stereochemical Course and Mechanisms of Nucleophilic Displacement Reactions at Phosphorus in Diastereomeric cis- and trans-2-Halogeno-4-methyl-1,3,2-dioxaphosphorinan-2-thiones: Experimental and DFT Studies

Molecules, 2021
Geometrical cis- and trans- isomers of 2-chloro-, 2-bromo- and 2-fluoro-4-methyl-1,3,2-dioxaphosphorinan-2-thiones were obtained in a diastereoselective way by (a) sulfurization of corresponding cyclic PIII-halogenides, (b) reaction of cyclic ...
Marian Mikołajczyk, Barbara Ziemnicka, Jan Krzywański, Marek Cypryk, Bartłomiej Gostyński   +4 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Metal catalyst-free N-allylation/alkylation of imidazole and benzimidazole with Morita–Baylis–Hillman (MBH) alcohols and acetates

Beilstein Journal of Organic Chemistry, 2023
A highly α-regioselective N-nucleophilic allylic substitution of cyclic MBH alcohols and acetates with imidazole or benzimidazole, in toluene at reflux with an azeotropic distillation, was successfully carried out with no catalysts or additives ...
Olfa Mhasni, Jalloul Bouajila, Farhat Rezgui   +2 more
doaj   +1 more source

Synthesis and characterization of novel substituted and cyclic benzoquinone derivatives

Synthetic Communications, 2016
Novel substituted benzoquinone compounds were synthesized from the reactions of p-chloranil and p-fluoranil with some thiols, amines, and diols in different reaction media. Interesting cyclic compounds like crown ether structures were obtained. The structures of all compounds were characterized by spectroscopic methods and microanalysis.
Ibiş, Cemi?, Sahinler Ayla, Sibel, Topaloglu, Esra, Yavuz, Şenol   +3 more
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Stabilization of angiotensin-(1-7) by key substitution with a cyclic non-natural amino acid [PDF]

, 2017
Angiotensin-(1-7) [Ang-(1-7)], a heptapeptide hormone of the renin-angiotensin-aldosterone system (RAAS), is a promising candidate as a treatment for cancer that reflects its antiproliferative and anti-angiogenic properties.
Wester, Anita, Paradisi, Francesca, Anita Wester, Chappell, Mark C., Marc Devocelle, Devocelle, Marc, E. Ann Tallant, Francesca Paradisi, Tallant, E. Ann, Patricia E. Gallagher, Gallagher, Patricia E., Tallant, Ann E., Mark C. Chappell   +12 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

An enzymatic mechanism for calcium current inactivation in dialysed Helix neurones [PDF]

, 1986
'Wash-out' and inactivation of the Ca current were examined in dialysed, voltage-clamped neurones of Helix aspersa under conditions that isolate the Ca current virtually free of other currents. EGTA or other internal Ca2+ chelators were routinely omitted
Chad, J.E., Eckert, R.
core  

Synthesis of an Eight-Membered Cyclic Pseudo-Dipeptide Using Ring Closing Metathesis [PDF]

, 2016
Ring closing metathesis of diallylglycine 6 provided cyclic Z-olefin 7 in 80% yield. The reaction was promoted by substitution of the amide nitrogen with the 2,4-dimethoxybenzyl group allowing for the required cis diallylglycine amide rotamer. Removal of
Allen B. Reitz (819813), Christopher J. Creighton (2725531)   +1 more
core   +3 more sources