Results 271 to 280 of about 215,802 (313)
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Cyclin-dependent-kinase-4-inhibitors/cyclin-dependent-kinase-6-inhibitors/fluconazole
Reactions Weekly, 2023openaire +1 more source
Cyclin-dependent-kinase-4-inhibitors/cyclin-dependent-kinase-6-inhibitors/fulvestrant
Reactions Weekly, 2023openaire +1 more source
Cyclin‐dependent kinase inhibitors for treating cancer
Medicinal Research Reviews, 2001AbstractCyclin dependent kinases (Cdks) are essential enzymes for the control of cell cycle progression. Inhibitors of cyclin‐dependent kinases are anticipated to possess therapeutic utility against a wide variety of proliferative diseases, especially cancer. The field of published small molecule Cdk inhibitors is briefly reviewed here as background to
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Cyclin-Dependent Kinase Inhibitor–Associated Thromboembolism
JAMA Oncology, 2019Sven R, Olson +2 more
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Trends in kinase drug discovery: targets, indications and inhibitor design
Nature Reviews Drug Discovery, 2021Misty M Attwood, Stefan Knapp
exaly
Cyclin-Dependent Kinase Inhibitors and Human Cancer
1998As tumor suppressor candidates, cyclin-dependent kinase (CDK) inhibitors have a simple, aesthetic quality. They act directly on the mechanism that drives cells through mitosis and DNA replication. Elimination of CDK inhibitor activity, by mutation for instance, should release CDKs from this form of regulation and remove one of the restraints on cell ...
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Assays for Cyclin-Dependent Kinase Inhibitors
2003Adrian M, Senderowicz, Tyler, Lahusen
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