Results 181 to 190 of about 28,898 (227)

Efficacy of CDK4/6 Inhibition in colorectal cancer and the role of p16 expression in predicting drug resistance. [PDF]

open access: yesCell Oncol (Dordr)
Schneider JS   +19 more
europepmc   +1 more source

Cyclin-dependent kinase inhibitor p16INK4a and telomerase may co-modulate endothelial progenitor cells senescence

Ageing Research Reviews, 2008
Endothelial cells (ECs) damage is an initial and pivotal step in the formation of atherosclerosis. Endothelial progenitor cells (EPCs), which have been considered as the precursor of ECs, can migrate and home to the site of injured ECs to divide into mature ECs and keep the integrity of the endothelial monolayer.
De-Guang, Yang   +2 more
openaire   +4 more sources

Increased expression of p16(INK4a) and p27(Kip1) cyclin-dependent kinase inhibitor genes in aging human kidney and chronic allograft nephropathy

American Journal of Kidney Diseases, 2003
The goal of the current study was to examine the potential value of p16(INK4a) and p27(Kip1) cyclin-dependent kinase inhibitor (CDKI) genes in the process of human kidney aging in vivo, and in the development of chronic allograft nephropathy (CAN).Expression of p16(INK4a) and p27(Kip1) CDKI genes was evaluated and compared in 20 normal human kidney ...
Archil B, Chkhotua   +9 more
openaire   +4 more sources

Familial uveal melanoma: absence of germline mutations involving the cyclin-dependent kinase-4 inhibitor gene (p16)

Ophthalmic Genetics, 1996
A D, Singh   +7 more
openaire   +4 more sources

Expression of the cyclin-dependent kinase inhibitor p16 in Alzheimerʼs disease

NeuroReport, 1996
Recent evidence indicates that an impairment of neuronal adaptive and reparative processes might be a key feature of the pathomechanism of Alzheimer's disease. Aberrations in the reparative neuronal response are likely to result from alterations of intracellular signal transduction cascades.
T, Arendt   +3 more
openaire   +2 more sources

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