Results 101 to 110 of about 242,314 (247)

Data from Post-transcriptional Modifications Contribute to the Upregulation of Cyclin D2 in Multiple Myeloma

, 2023
Irena Misiewicz-Krzemińska, María Eugenia Sarasquete, Carolina Vicente‐Dueñas, Patryk Krzemiński, Katarzyna Wiktorska, Luís A. Corchete, Dalia Quwaider, Elizabeta A. Rojas, Rocío Corral, Ana África Martín, Fernando Escalante, Abelardo Bárez, Juan Luis García, Isidro Sánchez‐García, Ramón García‐Sánz, Jesús F. San Miguel, Norma C. Gutiérrez   +16 more
openalex   +1 more source

Degradation strategy of cyclin D1 in cancer cells and the potential clinical application [PDF]

, 2022
Shuyi Chen, Ling Li
openalex   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Supplementary Figure 1 from Cyclin D1/Cyclin-Dependent Kinase 4 Interacts with Filamin A and Affects the Migration and Invasion Potential of Breast Cancer Cells

, 2023
Zhijiu Zhong, Wen-Shuz Yeow, Chunhua Zou, Richard Wassell, Chenguang Wang, Richard G. Pestell, Judy N. Quong, Andrew A. Quong   +7 more
openalex   +1 more source

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

Advanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen, Zening Huang, Rui Chang, Wei Gao, Yajing Qiu, Bin Sun, Chen Hua, Xiaoxi Lin   +7 more
wiley   +1 more source

Association of HAMP Expression and CD8+ T‐Cell Infiltration With Atezolizumab–Bevacizumab Response in Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
In hepatocellular carcinoma treated with atezolizumab–bevacizumab, responders showed RNA‐seq enrichment of immune and chemokine pathways with higher HAMP expression. In resected specimens, immunohistochemistry confirmed increased intratumoral CD8+ T‐cell density and hepcidin (HAMP), supporting HAMP plus CD8 as components of a composite predictor of ...
Shun Nakamura, Yuki Murakami, Yusuke Oshima, Takashi Masuda, Wataru Miyoshino, Hiroomi Takayama, Yoko Kawano, Teijiro Hirashita, Yuichi Endo, Masafumi Inomata   +9 more
wiley   +1 more source

Isolation and Characterization of the cDNA for an A-like Cyclin in Adiantum capillus-veneris L. [PDF]

, 1996
K. Uchida, Takamichi Muramatsu, Kosuke Tachibana, Takeo Kishimoto, M. Furuya   +4 more
openalex   +1 more source

Therapeutic Potential of the Cyclin-Dependent Kinase Inhibitor Flavopiridol on c-Myc Overexpressing Esophageal Cancer [PDF]

, 2021
Md Sazzad Hassan, Nicholas Cwidak, Chloe Johnson, Silvio Däster, Serenella Eppenberger‐Castori, Niranjan Awasthi, Jun Li, Margaret A. Schwarz, Urs von Holzen   +8 more
openalex   +1 more source

Prognostic Significance of Portal Vein Tumor Thrombus in Pancreatic Ductal Adenocarcinoma Treated With Chemoradiotherapy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim To examine the significance of portal vein tumor thrombus (PVTT) as a prognostic factor for patients with pancreatic ductal adenocarcinoma (PDAC) treated with chemoradiotherapy (CRT) followed by surgery. Methods The study retrospectively examined 313 patients with borderline resectable (BR) or locally advanced (LA) PDAC who underwent CRT ...
Aoi Hayasaki, Motonori Nagata, Miki Usui, Hiroshi Imai, Yusuke Iizawa, Akihiro Tanemura, Yasuhiro Murata, Naohisa Kuriyama, Masashi Kishiwada, Shugo Mizuno   +9 more
wiley   +1 more source

Cell Cycle and Cancer: Genetic Analysis of the Role of Cyclin-dependent Kinases [PDF]

, 2005
Mariano Barbacid, Sagrario Ortega, Rocı́o Sotillo, Junko Odajima, Alberto Martín, David Santamarı́a, Pierre Dubus, Marcos Malumbres   +7 more
openalex   +1 more source