Results 71 to 80 of about 2,773,799 (223)

Cyclin D1 expression in prostate carcinoma

open access: yesBrazilian Journal of Medical and Biological Research, 2014
The purpose of this study was to investigate the relationship between cyclin D1 expression and clinicopathological parameters in patients with prostate carcinoma.
R.A. Pereira   +7 more
doaj   +1 more source

The cycline subalgebra of a Kumjian-Pask algebra [PDF]

open access: yesProc. Amer. Math. Soc. 145 (2017), no. 5, 1969-1980, 2016
Let $\Lambda$ be a row-finite higher-rank graph with no sources. We identify a maximal commutative subalgebra $\mathcal{M}$ inside the Kumjian-Pask algebra ${\rm KP}_R(\Lambda)$. We also prove a generalized Cuntz-Krieger uniqueness theorem for Kumjian-Pask algebras which says that a representation of ${\rm KP}_R(\Lambda)$ is injective if and only if it
arxiv  

Phosphorylation of cyclin O, a novel cyclin family protein containing a cyclin-like domain, is involved in the activation of cyclin-dependent kinase 2

open access: yesOncology Letters, 2014
Cell cycles, ordered series of events modulating cell growth and division, are tightly regulated by complexes containing cyclin-dependent kinases (CDKs) and cyclins. Cyclin O is a novel cyclin family protein which interacts with CDK2. However, the molecular effects of cyclin O on the activity of CDK2 have not been fully evaluated.
In-Sik Chung   +5 more
openaire   +4 more sources

Anticancer activity of calyx of Diospyros kaki Thunb. through downregulation of cyclin D1 via inducing proteasomal degradation and transcriptional inhibition in human colorectal cancer cells

open access: yesBMC Complementary and Alternative Medicine, 2017
Background Although it has been reported to contain high polyphenols, the pharmacological studies of the calyx of Diospyros kaki Thunb (DKC) have not been elucidated in detail.
Su Bin Park   +6 more
doaj   +1 more source

Cyclin G2 Inhibits Oral Squamous Cell Carcinoma Growth and Metastasis by Binding to IGFBP3 and Regulating the FAK-SRC-STAT Signaling Pathway

open access: yesFrontiers in Oncology, 2020
The cell cycle protein cyclin G2 is considered a tumor suppressor. However, its regulatory effects and potential mechanisms in oral cancers are not well understood.
Danning Wang   +8 more
doaj   +1 more source

Periodic higher rank graphs revisited [PDF]

open access: yesarXiv, 2014
Let $P$ be a finitely generated cancellative abelian monoid. A $P$-graph $\Lambda$ is a natural generalization of a higher rank graph. A pullback of $\Lambda$ is constructed by pulling it back over a given monoid morphism to $P$, while a pushout of $\Lambda$ is obtained by modding out its periodicity $\Per\Lambda$, which is deduced from a natural ...
arxiv  

Prediction of repurposed drugs for treating lung injury in COVID-19 [PDF]

open access: yesarXiv, 2020
Coronavirus disease (COVID-19) is an infectious disease discovered in 2019 and currently in outbreak across the world. Lung injury with severe respiratory failure is the leading cause of death in COVID-19, brought by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
arxiv  

SCF Fbx4/alphaB-crystallin cyclin D1 ubiquitin ligase: a license to destroy

open access: yesCell Division, 2007
Cyclin D1 is an allosteric regulator for cyclin-dependent kinases 4 and 6 (CDK4/6). The cyclin D/CDK4 kinase promotes G1/S transition through the posttranslational modification and the subsequent inactivation of the retinoblastoma (Rb) protein and ...
Lin Douglas I   +2 more
doaj   +1 more source

Bifurcation in cell cycle dynamics regulated by p53 [PDF]

open access: yesarXiv, 2014
We study the regulating mechanism of p53 on the properties of cell cycle dynamics in the light of the proposed model of interacting p53 and cell cycle networks via p53. Irradiation (IR) introduce to p53 compel p53 dynamics to suffer different phases, namely oscillating and oscillation death (stabilized) phases.
arxiv  

Brucine Inhibits the Proliferation of Human Lung Cancer Cell Line PC-9 
via Arresting Cell Cycle

open access: yesChinese Journal of Lung Cancer, 2014
Background and objective It has been proven that Cyclin D1 and Cyclin E are the important positive regulators of cell cycle, they are closely related to the tumor proliferation. The aim of this study is to explore the relationship between Brucine and the
Miao LI   +4 more
doaj   +1 more source

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