Results 331 to 340 of about 12,781,724 (361)

REV1 Loss Triggers a G2/M Cell-Cycle Arrest Through Dysregulation of Mitotic Regulators. [PDF]

Genes (Basel)
Buntin B, Guyette M, Gupta V, Ikeh K, Bhattacharya S, Lamkin EN, Lafuze A, Del Rio-Guerra R, Hong J, Zhou P, Chatterjee N.   +10 more
europepmc   +1 more source

Crystal structure of the 2W99 complex, displaying chain A (cyclin D) in green and chain B (CDK4) in cyan.

Ibrahim Khater (12700096), Aaya Nassar (12700099)   +1 more
openalex   +1 more source

IL-1β Controls Proliferation, Apoptosis, and Necroptosis Through the PI3K/AKT/Src/NF-κB Pathway in Leukaemic Lymphoblasts. [PDF]

Biomedicines
Victoria-Avila ZL, Reyes-Maldonado E, Domínguez-López ML, Vela-Ojeda J, Lozada-Ruiz A, Alemán OR, Lezama RA.   +6 more
europepmc   +1 more source

Root mean square fluctuation (RMSF) plots of chain A (cyclin D) and chain B (CDK4) in the 2W99 complex.

Ibrahim Khater (12700096), Aaya Nassar (12700099)   +1 more
openalex   +1 more source

Fedratinib reveals chemotherapeutic potential in esophageal squamous cell cancer. [PDF]

Front Pharmacol
Luo M, Zhu J, Yang Y, Liao C, Liu X, Tang M, Xu L, Zhong X, Ma Q, Guo X.   +9 more
europepmc   +1 more source

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Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B

Nature, 1990
CYCLINS are proteins synthesized during each cell cycle and abruptly destroyed in each mitosis. Cyclins have been implicated in the induction of mitosis and are associated with the serine-threonine protein kinase p34cdc2 as components of mitosis promoting factor (MPF).
J. Pines, T. Hunter
semanticscholar   +3 more sources

Cyclin D1 expression in B-cell lymphomas

Experimental Hematology, 2010
Cyclin D1, an important component of cell cycle machinery and a protein with known oncogenic potential, is downregulated in normal mature B lymphocytes. Its expression detected in a number of malignancies, including B-cell lymphomas, may be important for oncogenesis.In our work, we determined the level of cyclin D1 expression in various B-cell ...
Aleena, Gladkikh, Daria, Potashnikova, Elena, Korneva, Olga, Khudoleeva, Ivan, Vorobjev   +4 more
openaire   +2 more sources

Cyclin D1 Inhibits Mitochondrial Activity in B Cells

Cancer Research, 2011
Abstract Cyclin D1 is a cell cycle regulatory protein that acts at the G1-S transition, following its binding to and activation by the cyclin-dependent kinases 4 or 6. Cyclin D1 is absent from the entire B-cell lineage but is present in a large percentage of 2 types of malignant B-cell hemopathy—mantle cell lymphoma and multiple ...
G, Tchakarska, M, Roussel, X, Troussard, Sola, Brigitte   +3 more
openaire   +3 more sources

The expression of SOX11, cyclin D1, cyclin D2, and cyclin D3 in B-cell lymphocytic proliferative diseases

Medical Oncology, 2011
SOX11 is mainly correlated with embryo neurogenesis and remodeling of tissues. D cyclins (cyclin D1, cyclin D2, and cyclin D3) work in cell transformation. We assessed the expression of SOX11, cyclin D1, cyclin D2, and cyclin D3 mRNA in 152 patients with B-cell lymphocytic proliferative diseases (B-LPD) using qRT-PCR and we detected SOX11 protein using
Xin, Cao, Lei, Fan, Cheng, Fang, Dan-Xia, Zhu, Hua-Jie, Dong, Dong-Mei, Wang, Yin-Hua, Wang, Wei, Xu, Jian-Yong, Li   +8 more
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Factors controlling cyclin B expression

Plant Molecular Biology, 2000
Cyclins control the transition between the phases of the eukaryotic cell cycle as regulatory subunits of the cyclin-dependent kinases (CDKs). Phase-specific activation of the CDK is in part regulated by phase-specific expression of their cyclin component. In most eukaryotic cells including higher plant, B-type cyclin genes are expressed specifically at
openaire   +2 more sources