Results 351 to 360 of about 13,616,352 (396)

Mantle Cell Lymphoma of the Thyroid: A Rare Cause of Life‐Threatening Airway Compromise

open access: yes
The Kaohsiung Journal of Medical Sciences, EarlyView.
Kanokwan Kesornpatumanant   +3 more
wiley   +1 more source

Resistance mechanisms and clonal dynamics in mantle cell lymphoma treated with sequential BTKi and venetoclax therapy

open access: yesThe Journal of Pathology, EarlyView.
Abstract In recent years, targeted therapies have become the standard of care for refractory/relapsed mantle cell lymphoma (MCL). Although the mutational profile of MCL has been extensively studied, there is a lack of understanding of resistance mechanisms and genetic factors that impact the response to novel treatments.
Tamás László   +19 more
wiley   +1 more source

Mechanism of D-type cyclin recognition by the AMBRA1 E3 ligase receptor. [PDF]

open access: yesSci Adv
Wang Y   +8 more
europepmc   +1 more source

PD‐L1 Expression is Mediated by microRNA Processing, Wnt/β‐Catenin Signaling, and Chemotherapy in Wilms Tumor

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Inhibition of immune checkpoint proteins is effective in adult cancers but has shown limited efficacy in pediatric cancers. While factors regulating expression of immune checkpoint proteins such as PD‐L1 are well documented in adult cancers, their regulation is poorly understood in pediatric cancers.
Patricia D. B. Tiburcio   +8 more
wiley   +1 more source

P53 and anti‐p53 autoantibody complex versus anti‐p53 antibody as a biomarker for gastrointestinal cancer

open access: yesPrecision Medical Sciences, EarlyView.
This study compares the diagnostic value of the anti‐p53 autoantibody as potential biomarkers for gastrointestinal cancer with enzyme‐linked immunosorbent assay technique. Abstract Gastrointestinal tract cancer is among the most common types of cancer and includes colorectal cancer (CRC) and gastric cancer (GC).
V. Hamidi Sofiani   +7 more
wiley   +1 more source

Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons

open access: yesSmall Science, EarlyView.
This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong   +4 more
wiley   +1 more source

Exosome‐Based Theranostic for Gastrointestinal Cancer: Advances in Biomarker Discovery and Therapeutic Engineering

open access: yesSmall Methods, EarlyView.
This review explores the dual roles of exosomes in gastrointestinal (GI) cancers as diagnostic biomarkers and therapeutic agents. It highlights advancements in exosomal miRNAs, lncRNAs, circRNAs, and proteins for cancer detection and prognosis. The study also examines engineering strategies for exosome‐based drug delivery systems, their potential to ...
Mohit J. Mehta   +7 more
wiley   +1 more source

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