Results 361 to 370 of about 13,616,352 (396)

Hypoxic HPV-Positive Cancer Cells Are Particularly Sensitive to the Pro-Senescent Effects of B-MYB Repression Due to the Lack of Compensatory A-MYB Induction. [PDF]

J Med Virol
Velimirović M, Avenhaus A, Lohrey C, Bulkescher J, Hoppe-Seyler F, Hoppe-Seyler K.   +5 more
europepmc   +1 more source

Multi‐Omics Analysis of Ileal Mucosa and Mesentery Before and After Ileocecal Resection in Crohn's Disease

United European Gastroenterology Journal, EarlyView.
ABSTRACT Crohn's disease (CD), a type of inflammatory bowel disease (IBD), is a chronic disorder involving any part of the gastrointestinal tract. Ileocecal resection may serve as a more effective treatment option for early CD. However, the potential relationship and mechanisms between the ileocecum and remission induction of CD are still elusive.
Kai Xia, Yiran Jiao, Luoqiu Zhang, Renyuan Gao, Fangtao Wang, Yun Pan, Shuang Cui, Yin Lin, Tianqi Wu, Lin Li, Xiaocai Wu, Yu Ruan, Jing Sun, Lu Yin, Chunqiu Chen, Moubin Lin   +15 more
wiley   +1 more source

Plasticity of mitotic cyclins in promoting the G2-M transition. [PDF]

J Cell Biol
Crncec A, Lau HW, Ng LY, Ma HT, Mak JPY, Choi HF, Yeung TK, Poon RYC.   +7 more
europepmc   +1 more source

Progesterone Luteal Support in Natural Cycles for Unexplained Infertility: A Randomised Controlled Trial (The PiNC Trial)

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To compare the effect of luteal‐phase progesterone supplementation in natural cycles to expectant management on live birth rates in women with unexplained infertility (UI). Design An open‐label, parallel‐arm, single‐centre randomised controlled trial. Setting One tertiary NHS‐funded fertility unit.
Claudia Raperport, Elpiniki Chronopoulou, Aviva Petrie, Roy Homburg, Elizabeth Timlick, Sheetal Barhate, Kristina Sackett, Priya Bhide   +7 more
wiley   +1 more source

Niclosamide: CRL4^AMBRA1 mediated degradation of cyclin D1 following mitochondrial membrane depolarization. [PDF]

RSC Med Chem
Coomar S, Gasser JA, Słabicki M, Donovan KA, Fischer ES, Ebert BL, Gillingham D, Thomä NH.   +7 more
europepmc   +1 more source

F-box protein FBXO32 ubiquitinates and stabilizes D-type cyclins to drive cancer progression. [PDF]

Nat Commun
Li F, Yu H, Zhang Y, Ma Y, Chen X, Zhang J, Sun L, Guo R, Wu Y, Zheng P, Wang X, Bie P, He F, Zhang L, Xie C, Xiong H.   +15 more
europepmc   +1 more source

Baseline cell cycle and immune profiles indicate CDK4/6 inhibitor response in metastatic HR + /HER2- breast cancer. [PDF]

NPJ Breast Cancer
Tzetzo SL, Schultz E, Wang J, Rosenheck HR, Mahan S, Knudsen ES, Witkiewicz AK.   +6 more
europepmc   +1 more source

DDB1 engagement defines the selectivity of S656 analogs for cyclin K degradation over CDK inhibition. [PDF]

EMBO Rep
Moison C, Mendoza-Sanchez R, Gracias D, Schuetz DA, Spinella JF, Girard S, Thavonekham B, Chagraoui J, Durand A, Fortier S, MacRae T, Bonneil E, Rose Y, Mayotte N, Boivin I, Thibault P, Hébert J, Ruel R, Marinier A, Sauvageau G.   +19 more
europepmc   +1 more source

Rare Case of Mantle Cell Lymphoma With Multiple Rectal Lesions

United European Gastroenterology Journal, EarlyView.
Lumir Kunovsky, Eliska Tvrdikova, Jozef Michalka, Jan Trna   +3 more
wiley   +1 more source