Results 161 to 170 of about 63,908 (269)

Complex Interplay Between Obesity and BRCA1/2‐Associated Breast Cancer: An Overview

Obesity Reviews, EarlyView.
ABSTRACT The steadily increasing prevalence of obesity and its association with a growing number of malignancies, including breast cancer, has made this disease spectrum an urgent and critical public health priority, demanding immediate attention and comprehensive action.
Cinzia Giordano, Marianna Puzzo, Rocco Malivindi, Debora Cristofaro, Luca Gelsomino, Daniela Bonofiglio, Carlo Capalbo, Sebastiano Andò, Ines Barone, Stefania Catalano   +9 more
wiley   +1 more source

Hydrogen Peroxide Mediates Pharmacological Ascorbate Induced Radio-Sensitization of Pancreatic Cancer Cells by Enhancing G2-accumulation and Reducing Cyclin B1 Protein Levels. [PDF]

Radiat Res, 2023
O'Leary BR, Kalen AL, Pope AN, Goswami PC, Cullen JJ.   +4 more
europepmc   +1 more source

Cyclin B1 Expression in HeLa S3 Cells Studied by Flow Cytometry

, 1994
Steven W. Sherwood, Daphne F. Rush, Andrew L. Kung, Robert Schimke   +3 more
openalex   +1 more source

Suppression of cell cycle progression by Jun dimerization protein (JDP2) involves down-regulation of cyclin A2 [PDF]

, 2009
We report here a novel role for Jun dimerization protein-2 (JDP2) as a regulator of the progression of normal cells through the cell cycle. To determine the role of JDP2 in vivo, we generated Jdp2 knock-out (Jdp2KO) mice by targeting exon 1 to disrupt ...
Atsushi Yoshiki, Hitomi Hasegawa, Jianzhi Pan, Kazunari K. Yokoyama, Koji Nakade, Naoto Yamaguchi, Satoko Masuzaki, Takehide Murata, Yu-Chang Huang, Yuichi Obata   +9 more
core   +1 more source

Optimised Ribosome Profiling Reveals New Insights Into Translational Regulation in Synchronised Chlamydomonas reinhardtii Cultures

Plant, Cell &Environment, EarlyView.
ABSTRACT Deep sequencing of ribosome footprints, also known as ribosome profiling (Ribo‐seq), enables the quantification of mRNA translation and a comprehensive view of the translatome landscape. Here, we report an optimised Ribo‐seq protocol and analysis pipeline for the model green alga, Chlamydomonas reinhardtiii (Chlamydomonas).
Yen‐Ling Lin, Eva Yuhua Kuo, Shih‐Yi Wang, Chih‐Chi Lee, Su‐Chiung Fang   +4 more
wiley   +1 more source

Nuclear tension controls mitotic entry by regulating cyclin B1 nuclear translocation. [PDF]

J Cell Biol, 2022
Dantas M, Oliveira A, Aguiar P, Maiato H, Ferreira JG.   +4 more
europepmc   +1 more source

p53 regulates a G ₂ checkpoint through cyclin B1

, 1999
Steven A. Innocente, John Abrahamson, John Cogswell, Jonathan M. Lee   +3 more
openalex   +2 more sources

Evaluation of the Effects of Walnut Extract on the Cell Division G2/M Cyclin-Cyclin B1 in Breast Cancer Cells [PDF]

, 2016
Walnuts are rich in polyphenols and have potential for cancer prevention and treatment. Our lab has previously shown that a walnut extract (WE) is able to block the cell cycle at the S and G2 phases of cell division with a corresponding decrease in the ...
Shah, Savita Pinaki
core   +1 more source

PP2A Promotes the Symmetric Division of MUC1‐Dominant Cancer Stem‐Like Cells in Small Cell Lung Cancer

Advanced Science, Volume 12, Issue 25, July 3, 2025.
During the G2/M phase, mucin1 (MUC1) activates protein phosphatase 2A (PP2A), leading to reduced phosphorylation of protein kinase C ζ (PKCζ) and NUMB, which promotes symmetric division and expansion of cancer stem‐like cells (CSLCs), thereby driving tumorigenesis. Combined inhibition of the MUC1–PP2A axis using LB100/GO203 with etoposide restores PKCζ
Shengze Li, Xinran Dong, Kexing Gao, Yiyang Wang, Min Li, Huayun Deng, Shuangyu Ma, Yaping Lv, Wei Jin, Quanfu Li, Yuming Wang, Xiaodong Liao, Kangjing Bian, Aiwu Zhou, Chengping Hu, Lei Huang   +15 more
wiley   +1 more source

Novel Therapeutic Combination Targets the Growth of Letrozole-Resistant Breast Cancer through Decreased Cyclin B1. [PDF]

Nutrients, 2023
Patel JR, Banjara B, Ohemeng A, Davidson AM, Boué SM, Burow ME, Tilghman SL.   +6 more
europepmc   +1 more source