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The Dual Face of Cyclin B1

Trends in Plant Science, 2018
Although widely used as a marker for cell proliferation, CYCB1;1 expression is also strongly induced in cells that suffer from DNA damage. Recently, this enigmatic dual expression pattern has been resolved by proving that CYCB1;1 promotes DNA repair. This has consequences for using CYCB1;1 as a cell cycle reporter.
Arp, Schnittger, Lieven, De Veylder
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Cyclin A and cyclin B1 overexpression in differentiated thyroid carcinoma

Medical Oncology, 2011
Approximately 30% of patients with thyroid nodules have indeterminate or suspicious fine-needle aspiration (FNA) biopsy results. These patients usually undergo thyroidectomy because of cancer risk. Our aim was to determine diagnostic value of cyclin A and cyclin B1 immunohistochemistry added to routine cytology and their expression on histological ...
Asli, Nar   +3 more
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Overexpression of cyclin B1 in human colorectal cancers

Journal of Cancer Research and Clinical Oncology, 1997
The expression of the human cyclin B1 gene was investigated with Western blot analysis in human colorectal carcinomas and in adjacent non-neoplastic colorectal mucosas. Out of 41 cancers, 36 (88% of patients) showed much higher expression of cyclin B1 than did the non-neoplastic mucosa.
A, Wang   +4 more
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