Cyclin B1 expression as an independent prognostic factor for lung adenocarcinoma and its potential pathways. [PDF]
Li Y+9 more
europepmc +1 more source
TP53‐Mutated Acute Myeloid Leukemia: Unanswered Questions
ABSTRACT TP53‐mutated acute myeloid leukemia (AML) remains one of the most treatment‐resistant hematologic malignancies, with poor overall survival despite advancements in therapeutic strategies. The loss of functional p53 compromises DNA repair, apoptosis, and genomic stability, rendering both conventional and novel therapies largely ineffective. This
Antonella Bruzzese+11 more
wiley +1 more source
GPx3 knockdown inhibits the proliferation and DNA synthesis and enhances the early apoptosis of human spermatogonial stem cells via mediating CXCL10 and cyclin B1. [PDF]
Wu S, Cheng Z, Peng Y, Cao Y, He Z.
europepmc +1 more source
Mitotic arrest induced by XK469, a novel antitumor agent, is correlated with the inhibition of cyclin B1 ubiquitination [PDF]
Hong Lin+5 more
openalex +1 more source
Lactate, beyond a metabolic byproduct, regulates immunity and inflammation, linked to cardiovascular diseases (CVD) via metabolic reprogramming. Lactylation, a lactate‐driven epigenetic mark, modulates gene expression in fibrosis, lipid disorders, and CVD progression.
Mengyang Song+3 more
wiley +1 more source
Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-PI3K-Cdk1/Cyclin B1 axis. [PDF]
Zhou Y+6 more
europepmc +1 more source
Erratum: Polo-like kinase 1 phosphorylates cyclin B1 and targets it to the nucleus during prophase [PDF]
Fumiko Toyoshima-Morimoti+4 more
openalex +1 more source
Expression profiling of cyclin B1 and D1 in cervical carcinoma.
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Zhao, M.+8 more
openaire +2 more sources
Transforming Growth Factor‐β Pathway: Biological Functions and Therapeutic Targets
Natural compounds modulate the TGF‐β pathway, which acts as both a tumor suppressor and promoter during cancer progression. Agents such as ginsenosides, halofuginone, and EGCG influence cell proliferation, apoptosis, and angiogenesis. These bioactive molecules may complement standard therapies, highlighting the need for advanced formulations ...
Reham Hassan Mekky+9 more
wiley +1 more source