Results 121 to 130 of about 2,874,801 (150)

Rh(III)-Catalyzed Asymmetric Synthesis of Axially Chiral Biindolyls by Merging C-H Activation and Nucleophilic Cyclization.

Journal of the American Chemical Society, 2019
Enantiomeric access to pentatomic biaryls is challenging due to their relatively low rotational barrier. Reported herein is the mild and highly enantioselective synthesis of 2,3'-biindolyls via underexplored integration of C-H activation and alkyne ...
M. Tian, Dachang Bai, G. Zheng, Junbiao Chang, Xingwei Li   +4 more
semanticscholar   +1 more source

Recent advances in nucleophile-triggered CO2-incorporated cyclization leading to heterocycles.

Chemical Society Reviews, 2019
Carbon dioxide (CO2) has emerged as a sustainable, feasible, abundant one-carbon synthon and displays great potential in the synthesis of heterocycles such as lactones, lactams, and 2-oxazolidinones, which are privileged motifs in pharmaceutical ...
Sheng Wang, C. Xi
semanticscholar   +1 more source

Metal-Catalyzed (4 + 3) Cyclization of Vinyl Aziridines with para-Quinone Methide Derivatives

ACS Catalysis, 2018
The development of (4 + 3) cyclizations of vinyl aziridines, especially catalytic asymmetric versions, is needed in organic synthesis. This report describes an iridium-catalyzed (4 + 3) cyclization of vinyl aziridines with para-quinone methide (p-QM ...
Fei Jiang, Fu-Ru Yuan, Lina Jin, Guang-Jian Mei, F. Shi   +4 more
semanticscholar   +1 more source

Unprecedented Cyclization Catalyzed by a Cytochrome P450 in Benzastatin Biosynthesis.

Journal of the American Chemical Society, 2018
Benzastatins have unique structures probably derived from geranylated p-aminobenzoic acids. The indoline and tetrahydroquinoline scaffolds are presumably formed by cyclization of the geranyl moiety, but the cyclization mechanism was unknown.
Hayama Tsutsumi, Yohei Katsuyama, M. Izumikawa, M. Takagi, M. Fujie, N. Satoh, K. Shin‐ya, Y. Ohnishi   +7 more
semanticscholar   +1 more source

Internal Oxidant-Triggered Aerobic Oxygenation and Cyclization of Indoles under Copper Catalysis.

Angewandte Chemie, 2016
A concise synthesis of pyrazolo[1,5-a]indole derivatives by copper-catalyzed aerobic oxygenation and cyclization of indoles with oxime acetates is described.
Huawen Huang, Jinhui Cai, Xiaochen Ji, Fuhong Xiao, Ya Chen, G. Deng   +5 more
semanticscholar   +1 more source

Gold-Catalyzed Asymmetric Intramolecular Cyclization of N-Allenamides for the Synthesis of Chiral Tetrahydrocarbolines.

Angewandte Chemie, 2017
Highly enantioselective gold-catalyzed intramolecular cyclization of N-allenamides was implemented by utilizing a designed chiral sulfinamide phosphine ligand (PC-Phos).
Yidong Wang, Peichao Zhang, Xiaoyu Di, Q. Dai, Zhan-Ming Zhang, Junliang Zhang   +5 more
semanticscholar   +1 more source

Control over Organometallic Intermediate Enables Cp*Co(III) Catalyzed Switchable Cyclization to Quinolines and Indoles

, 2016
Achieving controllable C–H functionalization to elaborate valuable compounds from simple chemicals is attractive and highly desirable, especially if nonprecious transition metal catalysts can be used.
Qingquan Lu, Suhelen Vásquez-Céspedes, T. Gensch, F. Glorius   +3 more
semanticscholar   +1 more source

Electrochemical Synthesis of Polycyclic N-Heteroaromatics through Cascade Radical Cyclization of Diynes

, 2017
An electrochemical cyclization reaction of easily available urea-tethered diynes has been developed for the synthesis of nitrogen-doped polycyclic aromatic hydrocarbons (PAHs).
Z. Hou, Zhongyi Mao, Jinshuai Song, Hai‐Chao Xu   +3 more
semanticscholar   +1 more source

Cobalt-Catalyzed Cyclization of Aliphatic Amides and Terminal Alkynes with Silver-Cocatalyst.

Journal of the American Chemical Society, 2015
A new method of cobalt-catalyzed synthesis of pyrrolidinones from aliphatic amides and terminal alkynes was discovered through a C-H bond functionalization process on unactivated sp(3) carbons with the silver cocatalyst using a bidentate auxiliary.
Jitan Zhang, Hui Chen, Cong Lin, Zhanxiang Liu, Chen Wang, Yuhong Zhang   +5 more
semanticscholar   +1 more source

Catalytic Asymmetric [4+1] Cyclization of ortho‐Quinone Methides with 3‐Chlorooxindoles

, 2017
In this work, we established catalytic asymmetric [4+1] cyclization of ortho-quinone methides (o-QMs) with 3-chlorooxindoles and a catalytic asymmetric domino oxidation/[4+1] cyclization reaction of 2-alkyl phenols with 3-chlorooxindoles, which ...
Xiao-Li Jiang, Si-Jia Liu, Yunjang Gu, Guang-Jian Mei, F. Shi   +4 more
semanticscholar   +1 more source