Multifunctional cytochrome P450 orchestrates radical cleavage and non-radical cyclization in 5-oxaindolizidine biosynthesis. [PDF]
Zhang K+13 more
europepmc +1 more source
Variations in density of coat during the life cycle of Sorex araneus araneus L. [PDF]
Stanisław Borowski
openalex +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
A convergent synthetic approach to the tetracyclic core framework of khayanolide-type limonoids. [PDF]
Zhang Z, Hu J, Ding H, Zhang L, Rao P.
europepmc +1 more source
Levels of Thyroid and Thyrotrophic Hormones in the Blood of Rats at Various Stages of the Œstrous Cycle [PDF]
Fouad M. Soliman, HELMY M. BADAWI
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Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
Synthesis of benzoheterocycles by palladium-catalyzed migratory cyclization through an unexpected reaction cascade. [PDF]
Li WC+7 more
europepmc +1 more source
The level of sex hormones during estrous cycle in the cow
Akira Ogasa, M. Yamauchi
openalex +2 more sources
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Peptide Recognition Sequence Guides Catalytic Side Chain Cross-Linking of Plant Peptides by Copper-Dependent Cyclases. [PDF]
Lima ST+6 more
europepmc +1 more source