Results 241 to 250 of about 831,285 (343)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Recent advances in Norrish-Yang cyclization and dicarbonyl photoredox reactions for natural product synthesis. [PDF]

Beilstein J Org Chem
Luo PX, Yang JX, Fu SM, Liu B.
europepmc   +1 more source

A Narrative Review of Life Cycle Assessments of Electric Vehicles: Methodological Challenges and Global Implications

Monika Zajemska, Anna Poskart, Andrzej Skibiński, Magdalena Skrzyniarz, J. Rzącki   +4 more
openalex   +1 more source

Strength and Fractal Damage Characteristics of Cement-Coal Slag Stabilized Soil under Freeze-thaw Cycles [PDF]

Kun Ren, Min Shi, M.T. Liang
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Ribosomal Synthesis of Topologically Defined Thioisoindole-Bridged Bicyclic Peptides. [PDF]

Angew Chem Int Ed Engl
Zhang Y, Vinogradov AA, Sun Y, Suga H.
europepmc   +1 more source

Simulation of extreme functionals in meteoceanic data: Application to surge evolution over tidal cycles [PDF]

Nathan Gorse, Olivier Roustant, Jérémy Rohmer, Déborah Idier   +3 more
openalex   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Unified Asymmetric Synthesis of Aryltetralin Lactone Cyclolignans via Conformation-Assisted Radical C-H Cyclization. [PDF]

JACS Au
Yin R, Wang X, Zhou R, Zhu L, Huang J.
europepmc   +1 more source

Innovative Bioenergy Systems in Action : The Mureck bio-Energy Cycle: Synergistic Effects and Socio-economic, Political and Sociocultural Aspects of Rural Bioenergy Systems

, 2005
Mihai Tomescu
openalex   +1 more source