Results 31 to 40 of about 831,285 (343)
Domino alkylation-cyclization reaction of propargyl bromides with thioureas/thiopyrimidinones: A new facile synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones [PDF]
, 2009 A new synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones was developed as a domino alkylation-cyclization reaction of propargyl bromides with thioureas and thio¬pyrimidinones, respectively.
Bernardini, Martina +3 more
core +1 more source
Cyclic Peptoid-Peptide Hybrids as Versatile Molecular Transporters
Frontiers in Chemistry, 2021 Addressing intracellular targets is a challenging task that requires potent molecular transporters capable to deliver various cargos. Herein, we report the synthesis of hydrophobic macrocycles composed of both amino acids and peptoid monomers. The cyclic
Claudine Nicole Herlan +6 more
doaj +1 more source
A Generalized Theory of DNA Looping and Cyclization [PDF]
, 2009 We have developed a generalized semi-analytic approach for efficiently computing cyclization and looping $J$ factors of DNA under arbitrary binding constraints. Many biological systems involving DNA-protein interactions impose precise boundary conditions
Meiners, Jens-Christian +2 more
core +2 more sources
Enzymatic Bromocyclization of α‐ and γ‐Allenols by Chloroperoxidase from Curvularia inaequalis
ChemistryOpen, 2022 Vanadate‐dependent chloroperoxidase from Curvularia inaequalis catalyzes 5‐endo‐trig bromocyclizations of α‐allenols to produce valuable halofunctionalized furans as versatile synthetic building blocks. In contrast to other haloperoxidases, also the more
Janne M. Naapuri +3 more
doaj +1 more source
A generalized theory of semiflexible polymers [PDF]
, 2005 DNA bending on length scales shorter than a persistence length plays an integral role in the translation of genetic information from DNA to cellular function. Quantitative experimental studies of these biological systems have led to a renewed interest in
B. Alberts +10 more
core +3 more sources
Cyclic β-glucans at the bacteria–host cells interphase: One sugar ring to rule them all [PDF]
, 2018 Cyclic β‐1,2‐D‐glucans (CβG) are natural bionanopolymers present in the periplasmic space of many Proteobacteria. These molecules are sugar rings made of 17 to 25 D‐glucose units linked exclusively by β‐1,2‐glycosidic bonds.
Arce Gorvel, Vilma +4 more
core +1 more source
ReactionsAzaoxyallyl cations, as novel and versatile three-atom components, have been widely utilized in cycloaddition reactions, with the competition between O- and N-cyclization pathways remaining a key research focus.
Wei Zhou +4 more
doaj +1 more source
Recent Advances in the Biosynthesis of Carbazoles Produced by Actinomycetes
Biomolecules, 2020 Structurally diverse carbazole alkaloids are valuable due to their pharmaceutical properties and have been isolated from nature. Experimental knowledge on carbazole biosynthesis is limited. The latest development of in silico analysis of the biosynthetic
Masaya Kobayashi, Tomohisa Kuzuyama
doaj +1 more source
The iso-Nazarov reaction [PDF]
, 2017 The construction of five-membered rings is essential in organic chemistry. In this context, pentannulation reactions that provide a straightforward access to cyclopentenones are of particular interest, as these structures are not only embedded in ...
Marsili, Lucía A. +2 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar +8 more
wiley +1 more source