Results 11 to 20 of about 3,190 (169)

Synthesis and investigation on optical and electrochemical properties of 2,4-diaryl-9-chloro-5,6,7,8-tetrahydroacridines

Beilstein Journal of Organic Chemistry, 2021
A facile synthesis of 2,4-diaryl-9-chloro-5,6,7,8-tetrahydroacridine derivatives is reported which is based on POCl3-mediated cyclodehydration followed by double Suzuki–Miyaura cross-coupling.
Najeh Tka, Mohamed Adnene Hadj Ayed, Mourad Ben Braiek, Mahjoub Jabli, Peter Langer   +4 more
doaj   +1 more source

CYCLIZATION AND HYDROGENATION OF (+)-CITRONELLAL TO MENTHOLS OVER ZnBr₂ AND Ni CATALYSTS SUPPORTED ON γ-Al₂O₃

Indonesian Journal of Chemistry, 2010
Two steps transformation of (+)-citronellal, cyclization and hydrogenation, on ZnBr2/γ-Al2O3 and Ni/γ-Al2O3 catalyst have been realized with the selectivity to cyclization products (isopulegols) was very high (yield up to ~92.58%) over ZnBr2/γ-Al2O3 ...
Elvina Dhiaul Iftitah, M. Muchalal, Wega Trisunaryanti, Ria Armunanto   +3 more
doaj   +1 more source

Synthesis and Biological Activities of Pyrazino[1,2-a]indole and Pyrazino[1,2-a]indol-1-one Derivatives

Pharmaceuticals, 2021
This review concerns the synthesis and biological activities of pyrazino[1,2-a]indoles and pyrazino[1,2-a]indol-1-ones reported since 1997 and the discovery of biological activity of pyrazinoindole derivatives.
Kena Zhang, Christine Tran, Mouad Alami, Abdallah Hamze, Olivier Provot   +4 more
doaj   +1 more source

Changing the topology of protein backbone: the effect of backbone cyclization on the structure and dynamics of a SH3 domain

Frontiers in Chemistry, 2015
Understanding of the effects of the backbone cyclization on the structure and dynamics of a protein is essential for using protein topology engineering to alter protein stability and function.
Frank H Schumann, Ranjani eVaradan, Praveen Pudiavettil Tayakuniyil, Jennifer Hall Grossman, Julio A Camarero, Julio A Camarero, David eFushman   +6 more
doaj   +1 more source

Cyclic Peptoid-Peptide Hybrids as Versatile Molecular Transporters

Frontiers in Chemistry, 2021
Addressing intracellular targets is a challenging task that requires potent molecular transporters capable to deliver various cargos. Herein, we report the synthesis of hydrophobic macrocycles composed of both amino acids and peptoid monomers. The cyclic
Claudine Nicole Herlan, Anna Meschkov, Anna Meschkov, Ute Schepers, Ute Schepers, Stefan Bräse, Stefan Bräse   +6 more
doaj   +1 more source

Nucleophilic and electrophilic cyclization of N-alkyne-substituted pyrrole derivatives: Synthesis of pyrrolopyrazinone, pyrrolotriazinone, and pyrrolooxazinone moieties

Beilstein Journal of Organic Chemistry, 2017
Intramolecular nucleophilic and electrophilic cyclization of N-alkyne-substituted pyrrole esters is described. Efficient routes towards the synthesis of pyrrolopyrazinone, pyrrolotriazinone and pyrrolooxazinone have been developed.
Işıl Yenice, Sinan Basceken, Metin Balci   +2 more
doaj   +1 more source

Enzymatic Bromocyclization of α‐ and γ‐Allenols by Chloroperoxidase from Curvularia inaequalis

ChemistryOpen, 2022
Vanadate‐dependent chloroperoxidase from Curvularia inaequalis catalyzes 5‐endo‐trig bromocyclizations of α‐allenols to produce valuable halofunctionalized furans as versatile synthetic building blocks. In contrast to other haloperoxidases, also the more
Janne M. Naapuri, Philip K. Wagner, Prof. Dr. Frank Hollmann, Prof. Dr. Jan Deska   +3 more
doaj   +1 more source

Recent Advances in the Biosynthesis of Carbazoles Produced by Actinomycetes

Biomolecules, 2020
Structurally diverse carbazole alkaloids are valuable due to their pharmaceutical properties and have been isolated from nature. Experimental knowledge on carbazole biosynthesis is limited. The latest development of in silico analysis of the biosynthetic
Masaya Kobayashi, Tomohisa Kuzuyama
doaj   +1 more source

Substituents Regulate the Cyclization of Conjugated Alkynes to Accurately Construct Cyclo-(E)-[3]dendralenes

Molecules, 2023
Substituent-regulated cyclization of conjugated alkynes with acid catalysis was developed in this paper, and it provides a straightforward synthesis of cyclic-(E)-[3]dendralenes.
Yun-Tao Xia, Ya-Xin Li, Tong-Tong Bi, Wei Lian, Xia Wang, Meng Yan, Tao Guo   +6 more
doaj   +1 more source

Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones

Molecules, 2005
Three convenient methods of reduction of the nitro group of 5-nitroimidazoles and 5-nitrothiazole that bear a diethylmethylene malonate group in an ortho-like position with respect to the nitro group and cyclization of the resulting amino derivatives are
Patrice Vanelle, Michel P. Crozet, Pascal George, Maxime D. Crozet   +3 more
doaj   +1 more source