Results 1 to 10 of about 153,473 (240)

Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis. [PDF]

Journal of the American Chemical Society, 2016
The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the
Kärkäs, Markus D., Porco, John A., Stephenson, Corey R.J.   +2 more
core   +18 more sources

Cycloadditions as a Sweet Route to ‘Double C-Glycosylation’ [PDF]

Biomolecules
Pharmaceuticals, such as the antibiotic erythromycin, and sodium-dependent glucose transporter (SGLT1 & SGTL2) inhibitors such as Bexagliflozin (diabetes) and Sotagliflozin (heart disease), are often sugar-decorated (glycosylated). Glycosylation is a key
Kevin P. P. Mahoney, Rosemary Lynch, Rhea T. Bown, Sunil V. Sharma, Piyasiri Chueakwon, G. Richard Stephenson, David B. Cordes, Alexandra M. Z. Slawin, Rebecca J. M. Goss   +8 more
doaj   +2 more sources

Pericyclases for cycloaddition

National Science Review, 2022
Focusing on the cycloadditions, which have been widely utilized in total synthesis, this perspective reviews the flourish research of pericyclase for cycloaddition and discusses existing challenges.
Zhang, Bo, Ge, Hui Ming
openaire   +2 more sources

Exploring Pyrrolo-Fused Heterocycles as Promising Anticancer Agents: An Integrated Synthetic, Biological, and Computational Approach

Pharmaceuticals, 2023
Five new series of pyrrolo-fused heterocycles were designed through a scaffold hybridization strategy as analogs of the well-known microtubule inhibitor phenstatin.
Roxana-Maria Amărandi, Maria-Cristina Al-Matarneh, Lăcrămioara Popovici, Catalina Ionica Ciobanu, Andrei Neamțu, Ionel I. Mangalagiu, Ramona Danac   +6 more
doaj   +1 more source

Synthesis of 4-Arylselanyl-1H-1,2,3-triazoles from Selenium-Containing Carbinols

Molecules, 2021
In this work, we present a simple way to achieve 4-arylselanyl-1H-1,2,3-triazoles from selenium-containing carbinols in a one-pot strategy. The selenium-containing carbinols were used as starting materials to produce a range of selanyl-triazoles in ...
Francesca Begini, Renata A. Balaguez, Allya Larroza, Eric F. Lopes, Eder João Lenardão, Claudio Santi, Diego Alves   +6 more
doaj   +1 more source

Poly(ionic liquid)s for Photo‐Driven CO2 Cycloaddition: Electron Donor–Acceptor Segments Matter

Advanced Science, 2023
CO2 cycloaddition with epoxides is a key catalytic procedure for CO2 utilization. Several metal‐based catalysts with cocatalysts are developed for photo‐driven CO2 cycloaddition, while facing difficulties in product purification and continuous reaction ...
Xu Fang, Li Yang, Zhangben Dai, Die Cong, Daoyuan Zheng, Tie Yu, Rui Tu, Shengliang Zhai, Junxia Yang, Fengling Song, Hao Wu, Wei‐qiao Deng, Chengcheng Liu   +12 more
doaj   +1 more source

Synthesis of 5,6-Dihydropyrazolo[5,1-a]isoquinolines through Tandem Reaction of C,N-Cyclic Azomethine Imines with α,β-Unsaturated Ketones

Molecules, 2023
An innovative and efficient approach has been developed for the synthesis of 5,6-dihydropyrazolo[5,1-a]isoquinolines. This one-pot tandem reaction involves the reaction of C,N-cyclic azomethine imines with α,β-unsaturated ketones, using K2CO3 as the base
Young Jae Yun, Sung-Gon Kim
doaj   +1 more source

Cycloaddition Chemistry of a Silylene‐Nickel Complex toward Organic π‐Systems: From Reversibility to C−H Activation [PDF]

, 2020
The versatile cycloaddition chemistry of the Si−Ni multiple bond in the acyclic (amido)(chloro)silylene→Ni0 complex 1, [(TMSL)ClSi→Ni(NHC)2] (TMSL=N(SiMe3)Dipp; Dipp=2,6‐iPr2C6H4; NHC=C[(iPr)NC(Me)]2), toward unsaturated organic substrates is reported ...
Drieß, Matthias, Hadlington, Terrance J., Kostenko, Arseni   +2 more
core   +1 more source

Electrochemical Synthesis of Isoxazoles and Isoxazolines via Anodic Oxidation of Oximes

ChemElectroChem, 2023
Isoxazol(in)es are widely featured structural motifs in natural products, agrochemicals, and pharmaceuticals. The first intermolecular approach for a direct electrochemical synthesis from readily available aldoximes is reported.
Silja Hofmann, Johannes Winter, Tobias Prenzel, Dr. María deJesús Gálvez‐Vázquez, Prof. Dr. Siegfried R. Waldvogel   +4 more
doaj   +1 more source

Organocatalysis with carbon nitrides

Science and Technology of Advanced Materials, 2023
Carbon nitrides, a distinguished class of metal-free catalytic materials, have presented a good potential for chemical transformations and are expected to become prominent materials for organocatalysis.
Sujanya Maria Ruban, Kavitha Ramadass, Gurwinder Singh, Siddulu Naidu Talapaneni, Gunda Kamalakar, Chandrakanth Rajanna Gadipelly, Lakshmi Kantham Mannepalli, Yoshihiro Sugi, Ajayan Vinu   +8 more
doaj   +1 more source