Results 101 to 110 of about 140,419 (292)

Halogenation effects in Intramolecular Furan Diels-Alder reactions:broad scope synthetic and computational studies [PDF]

, 2013
For the first time a comprehensive synthetic and computational study of the effect of halogen substitution on both furan and dienophile for the intramolecular Furan Diels-Alder (IMDAF) reaction has been undertaken.
Bebbington, Magnus William Paul, Paterson, Martin, Rae, Robert, Zurek, Justyna Marlena   +3 more
core   +1 more source

The regioselective synthesis of spirooxindolo pyrrolidines and pyrrolizidines via three-component reactions of acrylamides and aroylacrylic acids with isatins and α-amino acids

Beilstein Journal of Organic Chemistry, 2014
The regioselective three-component condensation of azomethine ylides derived from isatins and α-amino acids with acrylamides or aroylacrylic acids as dipolarophiles has been realized through a one-pot 1,3-dipolar cycloaddition protocol.
Tatyana L. Pavlovskaya, Fedor G. Yaremenko, Victoria V. Lipson, Svetlana V. Shishkina, Oleg V. Shishkin, Vladimir I. Musatov, Alexander S. Karpenko   +6 more
doaj   +1 more source

Extracellular Vesicle Crosslinkers Constructing Hydrogels with Stress‐Relaxation and Bioactive Protein Modification

Advanced Materials Interfaces, EarlyView.
Extracellular vesicles (EVs) are functionalized and used as crosslinkers to construct hydrogels, compatible with common crosslinking chemistries in biomaterial scaffolds. EV crosslinkers provided stress relaxation properties, promoting cell growth. They also enabled efficient protein delivery while maintaining biological activity, as VEGF‐loaded EV ...
Lufeng Shi, Yanzhen Jing, Haowen Lu, Fanxuan Zhao, Mengying An, Shuiling Jin, Chang Gao, Yongdong Dai, Yinxin Zhu, Shuxu Yang, Songying Zhang, Xuesong Ye, Xiujun Cai, Yifan Wang, Shangjing Xin   +14 more
wiley   +1 more source

Isolation of bis(copper) key intermediates in Cu-catalyzed azide-alkyne "click reaction". [PDF]

, 2015
The copper-catalyzed 1,3-dipolar cycloaddition of an azide to a terminal alkyne (CuAAC) is one of the most popular chemical transformations, with applications ranging from material to life sciences.
Bertrand, Guy, Jin, Liqun, Melaimi, Mohand, Tolentino, Daniel R   +3 more
core   +2 more sources

Toward Personalized Stationary Chromatography Phases: Equipping Commercial Silica Phases with Selected Peptide‐Based Binding Domains to Tailor Affinity

Advanced Materials Interfaces, EarlyView.
The 7‐mer peptide motifs QFFLFFQ, QFFEFFQ, and QFQQSFF, known as good, medium, and poor binders for the photosensitizers m‐THPC and Chlorin E6 are covalently immobilized on commercial amino‐functionalized silica particles by inverse electron‐demand Diels‐Alder ligation.
Steffen A. Busche, Lukas D. Bangert, Raoul D. Brand, Tommy Kröger, Enrico Heyl, Hans G. Börner   +5 more
wiley   +1 more source

Preparation of 4 '-spirocyclobutyl nucleoside analogues as novel and versatile adenosine scaffolds

, 2019
Despite the large variety of modified nucleosides that have been reported, the preparation of constrained 4 '-spirocyclic adenosine analogues has received very little attention.
De Vleeschouwer, Freija, Kong, Hanchu, Meerpoel, Lieven, Pande, Vineet, Sun, Weimei, Thuring, Jan Willem, Van Hecke, Kristof, Verhoeven, Jonas, Verniest, Guido, Vos, Ann, Wu, Tongfei   +10 more
core   +1 more source

Double‐Sided Control of Product Type Preference in the Visible‐Light Initiated Reaction of 1,3‐Dicarbonyl Compounds with Alkenes

Advanced Synthesis &Catalysis, EarlyView.
Abstract The demonstrated light‐initiated addition of radicals formed on an active methylene group to styrene derivatives exhibits a product selectivity influenced by the presence of a protic solvent. Under protic conditions, the predominant products are branched compounds with the alkene moiety attached to the methylene group.
Małgorzata Pałyga, Jan Rzepiela, Sebastian Baś   +2 more
wiley   +1 more source

Gram‐Scale Photocatalysis with a Stable and Recyclable Chromium(III) Photocatalyst in Acetonitrile and in Water

Advanced Synthesis &Catalysis, EarlyView.
Abstract The use of stable photosensitizers made on a multigram‐scale from cheap and available starting materials offers an extraordinary opportunity to translate small‐scale proof‐of‐concept photoreactions to widespread applications in non‐specialized laboratories, thereby promoting the implementation of light‐driven syntheses.
Steven Sittel, Julian Neuner, Jonas M. Grenz, Christoph Förster, Robert Naumann, Katja Heinze   +5 more
wiley   +1 more source

Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model. [PDF]

, 2013
The pyridine heterocycle continues to play a vital role in the development of human medicines. More than 100 currently marketed drugs contain this privileged unit, which remains highly sought after synthetically. We report an efficient means to access di-
Garg, Neil K, Goetz, Adam E
core  

Synthetic and computational studies on the tricarboxylate core of 6,7-dideoxysqualestatin H5 involving a carbonyl ylide cycloaddition–rearrangement [PDF]

, 2010
Reaction of diazodiketoesters 17 and 28 with methyl glyoxylate in the presence of catalytic rhodium(II) acetate generates predominantly the 6,8-dioxabicyclo[3.2.1]octanes 29 and 30, respectively.
Adamo, Aggarwal, Allinger, Angelastro, Armstrong, Armstrong, Azzouzi, Becke, Bhalay, Bierstedt, Blows, Bunte, Calter, Carolina Villalonga-Barber, Carreira, David M. Hodgson, Dawson, Ditchfield, Do, Dominey, Evans, Hasumi, Hirata, Hodgson, Hodgson, Hodgson, Hook, Jiang, Jonathan M. Goodman, Jorgensen, Kataoka, Labadie, Lee, London, Marten, Mehta, Naito, Nakamura, Nicewicz, Nicolaou, Padwa, Perlmutter, Pipek, Searle, Shimada, Sidebottom, Silvina C. Pellegrinet, Smith, Smith, Suffert, Tsubuki, Wang, Wang, Wasserman, Wolinski, Zhang, Zhao, Zhao   +57 more
core   +1 more source