Cycloadditions of cyclohexynes and cyclopentyne. [PDF]
, 2014 We report the strategic use of cyclohexyne and the more elusive intermediate, cyclopentyne, as a tool for the synthesis of new heterocyclic compounds. Experimental and computational studies of a 3-substituted cyclohexyne are also described.
Garg, Neil K +4 more
core +10 more sources
Topological classification of cycloadditions occurring on-surface and in the solid-state. [PDF]
Commun ChemLi J +15 more
europepmc +3 more sources
Poly(ionic liquid)s for Photo‐Driven CO2 Cycloaddition: Electron Donor–Acceptor Segments Matter
Advanced Science, 2023 CO2 cycloaddition with epoxides is a key catalytic procedure for CO2 utilization. Several metal‐based catalysts with cocatalysts are developed for photo‐driven CO2 cycloaddition, while facing difficulties in product purification and continuous reaction ...
Xu Fang +12 more
doaj +1 more source
Cycloaddition Chemistry of a Silylene‐Nickel Complex toward Organic π‐Systems: From Reversibility to C−H Activation [PDF]
, 2020 The versatile cycloaddition chemistry of the Si−Ni multiple bond in the acyclic (amido)(chloro)silylene→Ni0 complex 1, [(TMSL)ClSi→Ni(NHC)2] (TMSL=N(SiMe3)Dipp; Dipp=2,6‐iPr2C6H4; NHC=C[(iPr)NC(Me)]2), toward unsaturated organic substrates is reported ...
Drieß, Matthias +2 more
core +1 more source
Pericyclases for cycloaddition
National Science Review, 2022 Focusing on the cycloadditions, which have been widely utilized in total synthesis, this perspective reviews the flourish research of pericyclase for cycloaddition and discusses existing challenges.
Zhang, Bo, Ge, Hui Ming
openaire +2 more sources
On the strong difference in reactivity of acyclic and cyclic diazodiketones with thioketones: experimental results and quantum-chemical interpretation [PDF]
, 2015 The 1,3-dipolar cycloaddition of acyclic 2-diazo-1,3-dicarbonyl compounds (DDC) and thioketones preferably occurs with Z,Econformers and leads to the formation of transient thiocarbonyl ylides in two stages.
Holleman +8 more
core +4 more sources
Synthesis of 1,4-Disubstituted Mono and Bis-triazolocarbo-acyclonucleoside Analogues of 9-(4-Hydroxybutyl)guanine by Cu(I)-Catalyzed Click Azide-Alkyne Cycloaddition [PDF]
, 2011 A series of novel mono-1,2,3-triazole and bis-1,2,3-triazole acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine was prepared via copper(I)-catalyzed 1,3-dipolar cycloaddition of N-9 propargylpurine, N-1-propargylpyrimidines/as-triazine with the ...
Engels, Joachim W. +2 more
core +2 more sources
Beilstein Journal of Organic Chemistry, 2022 A convergent strategy for the synthesis of leustroducsins and phoslactomycins has been designed, relying on the synthesis and the coupling of three main fragments.
Anaïs Rousseau +2 more
doaj +1 more source
Discovery of new mutually orthogonal bioorthogonal cycloaddition pairs through computational screening. [PDF]
, 2015 Density functional theory (DFT) calculations and experiments in tandem led to discoveries of new reactivities and selectivities involving bioorthogonal sydnone cycloadditions.
Houk, KN +3 more
core +1 more source
Synthesis and antitumoral activity of novel biaryl hydroxy-triazole and fluorene-triazole hybrids [PDF]
Exploration of Drug ScienceAim: The development of selective and potent antitumor agents remains a significant challenge. This study aimed to synthesize and evaluate biaryl hydroxy-1,2,3-triazoles and 9H-fluorene-1,2,3-triazole hybrids, inspired by previously identified bioactive ...
David Chafi Zeitune +6 more
doaj +1 more source