Results 21 to 30 of about 2,089,289 (186)

Synthetic studies on the bioactive tetramic acid JBIR-22 using a late stage Diels-Alder reaction [PDF]

open access: yes, 2015
The authors would like to thank the following for funding: Cancer Research UK (grants C21383/A6950 and C483/A10706)A late stage Diels-Alder reaction is used to prepare a mixture of JBIR-22, a natural product from the Equisetin family of tetramic acids ...
Healy, A. R., Westwood, Nicholas James
core   +1 more source

On the Question of Zwitterionic Intermediates in the [3+2] Cycloaddition Reactions between Aryl Azides and Ethyl Propiolate

open access: yesMolecules, 2023
The molecular mechanism of the [3+2] cycloaddition reactions between aryl azides and ethyl propiolate was evaluated in the framework of the Molecular Electron Density Theory.
Ewa Dresler   +3 more
doaj   +1 more source

Intramolecular Imino Diels-Alder Reaction: Progress toward the Synthesis of Uncialamycin [PDF]

open access: yes, 2009
We herein described an intramolecular imino Diels-Alder reaction promoted with BF3.OEt2/DDQ affording substituted quinolines. Using this procedure, we prepared the chiral quitioline moiety of the uncialamycin, a new enediyne natural ...
Pierre van de Weghe   +5 more
core   +1 more source

[Bmim]Br Accelerated One-Pot Three-Component Cascade Protocol for the Construction of Spirooxindole–Pyrrolidine Heterocyclic Hybrids

open access: yesMolecules, 2020
Our synthetic approach for the assembly of structurally complex spirooxindole heterocyclic hybrids was based on an ionic liquid, [bmim]Br mediated one-pot three-component cascade reaction strategy involving 1,3-dipolar cycloaddition reaction of N-1-(2 ...
Raju Suresh Kumar   +4 more
doaj   +1 more source

The Cycloaddition of the Benzimidazolium Ylides with Alkynes: New Mechanistic Insights. [PDF]

open access: yesPLoS ONE, 2016
New insights concerning the reaction mechanism in the cycloaddition reaction of benzimidazolium ylides to activated alkynes are presented. The proposed pathway leading both to 2-(1H-pyrrol-1-yl)anilines and to pyrrolo[1,2-a]quinoxalin-4(5H)-ones involves
Costel Moldoveanu   +4 more
doaj   +1 more source

Efficient fabrication of oxazolidinones for the carboxylative cyclization with carbon dioxide

open access: yesJournal of CO2 Utilization, 2023
Overuse of fossil energy has accelerated the development of industrialization and improved the quality of human life. However, it also leads to the excessive emission of CO2, and the greenhouse effect is threatening global climate stability and human ...
Xin Yang   +5 more
doaj   +1 more source

Highly Efficient Construction of Sugar-Fused Spirochromanono Pyrrolidines/Pyrrolizidines/Thiolizidines via 1,3-Dipolar Cycloaddition of Azomethine Ylides

open access: yesSynOpen, 2017
A variety of sugar-fused chromanono pyrrolidines/pyrrolizidines/thiolizidines have been synthesized by intermolecular 1,3-dipolar cycloaddition reaction of azomethine ylides (generated from glucose aldehyde and different secondary amino acids) with ...
Sirisha Nallamala   +2 more
doaj   +1 more source

Ab initio study of the mechanism of formation of a spiro-Sn-heterocyclic ring compound by the cycloaddition reaction of H2C=Sn: and ethylene [PDF]

open access: yesJournal of the Serbian Chemical Society, 2019
X2C=Sn: (X = H, Me, F, Cl, Br, Ph, Ar…) are new species of chemistry. The cycloaddition reactions of X2C=Sn: is a new study field of stannylene chemistry.
Tan Xiaojun, Lu Xiuhui
doaj   +1 more source

Palladium-Catalyzed [3+2] Cycloaddition via Two-Fold 1,3-C(sp3)−H Activation [PDF]

open access: yes, 2020
Cycloaddition reactions provide an expeditious route to construct ring systems in a highly convergent and stereoselective manner. For a typical cycloaddition reaction to occur, however, the installation of multiple reactive functional groups (π-bonds ...
jin-quan, yu, Hojoon, Park
core   +2 more sources

Synthesis of Different Heterocyclic Compounds of Pharmaceutical Relevance [PDF]

open access: yes
This thesis describes the synthesis of different cyclic imines and the exploration of their reactivity with cyclopropenones and 1,3-dipoles,as well as an investigation of the chemistry of the products.
Khan, Musharraf Naveed
core   +3 more sources

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